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Associations Between Domain-specific Sedentary Behaviour And Perceived Cognitive Function Of Cancer Survivors

2024· article· en· W4402662775 on OpenAlexaff
Sarah Kanako O'Rourke, Allyson Tabaczynski, Golnaz Ghazinour, Natalie Cuda, Linda Trinh

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2024
Typearticle
Languageen
FieldMedicine
TopicCancer-related cognitive impairment studies
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsCognitionFunction (biology)Cancer survivorDomain (mathematical analysis)PsychologySedentary behaviorCancerGerontologyPhysical activityMedicineMathematicsPhysical medicine and rehabilitationBiologyInternal medicineNeuroscienceEvolutionary biology

Abstract

fetched live from OpenAlex

Cancer survivors spend the majority (~66%) of time in sedentary behaviours (SED), which can lead to deleterious health effects such as including cancer-related cognitive impairment (CRCI) that impact quality of life. Reducing SED has shown to reduce the impact of CRCI, however, the relationship between domain-specific SED and cognitive function in cancer survivors remains unknown. PURPOSE: To examine the associations between domain specific-SED and perceived cognitive function in cancer populations during the COVID-19 pandemic. METHODS: This study was a secondary analysis from an online survey in adult cancer survivors globally. Demographic (e.g., age, sex), and medical (e.g., cancer type) were self-reported. SED was assessed using the Domain-specific Sitting Time Questionnaire. Perceived cognitive function was assessed using the Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) scale, which comprised of four subscale domains (e.g., perceived cognitive abilities [PCA]). Linear regressions were used to examine the association between change in SED domains (i.e., total, transport, work, television, computer, leisure) and FACT-Cog scores. RESULTS: Participants (N = 393, Mage = 48.4 ± 0.8) were primarily post-treatment (61.6%), breast (26.8%) cancer survivors. Change in leisure-time SED was significantly associated with PCA scores (β = .10; 95% CI: 0.00, 0.02; p = .04), where decreasing leisure-time SED was associated with improvements on PCA. These results indicate that for a one-point change on PCA, participants would need to decrease their leisure-time SED by 125 min/day. Changes in other domain-specific SED did not result in significant improvements (p > 0.05) on the total FACT-Cog or subscales. CONCLUSIONS: A reduction in time spent on leisure-specific SED is associated with modest improvements in PCA. Interventions should consider reducing leisure-specific SED to enhance PCA. Future research should utilize longitudinal designs to supplement these findings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.053
Threshold uncertainty score0.767

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.313
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2024
Admission routes1
Has abstractyes

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