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Record W4402698034 · doi:10.1002/ijc.35182

Occupational exposure to radiofrequency electromagnetic fields and brain tumor risk: <scp>Application</scp> of the <scp>INTEROCC</scp> job‐exposure matrix

2024· article· en· W4402698034 on OpenAlexafffund
Maxime Turuban, Hans Kromhout, Javier Vila, Miquel Vallbona‐Vistós, Frank de Vocht, Isabelle Baldi, Lesley Richardson, Geza Benke, Daniel Krewski, Marie‐Élise Parent, Siegal Sadetzki, Brigitte Schlehofer, Joachim Schüz, Jack Siemiatycki, Martie van Tongeren, Alistair Woodward, Elisabeth Cardis, Michelle C. Turner

Bibliographic record

VenueInternational Journal of Cancer · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicElectromagnetic Fields and Biological Effects
Canadian institutionsInstitut National de la Recherche ScientifiqueUniversity of OttawaUniversité de Montréal
FundersGSM AssociationMcKee Medical Center FoundationNational Cancer InstituteNational Institute for Health Research Applied Research Collaboration WestHealth Research Council of New ZealandCancer Council NSWSocial Sciences and Humanities Research Council of CanadaNatural Sciences and Engineering Research Council of CanadaMary McClellan FoundationAgence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du TravailAgence Française de Sécurité Sanitaire de l'Environnement et du TravailCancer Research SocietyCanada Research ChairsGeneralitat de CatalunyaNational Institute for Health and Care ResearchWellington Medical Research FoundationUnion for International Cancer ControlJohannes Gutenberg-Universität MainzWaikato Medical Research FoundationMedical Research CouncilNational Health and Medical Research CouncilHealth and Safety ExecutiveFonds de Recherche du Québec - SantéMinisterio de Ciencia, Innovación y UniversidadesCentre International de Recherche sur le CancerWorld Health OrganizationAgencia Estatal de InvestigaciónCancer Council VictoriaEuropean Social FundCancer Society of New ZealandCanadian Institutes of Health Research
KeywordsConfidence intervalMedicineJob-exposure matrixLogistic regressionOdds ratioOccupational exposureInternal medicineEnvironmental health

Abstract

fetched live from OpenAlex

Radiofrequency electromagnetic fields (RF-EMF, 100 kHz to 300 GHz) are classified by IARC as possibly carcinogenic to humans (Group 2B). This study evaluates the potential association between occupational RF-EMF exposure and brain tumor risk, utilizing for the first time, a RF-EMF job-exposure matrix (RF-JEM) developed in the multi-country INTEROCC case-control study. Cumulative and time-weighted average (TWA) occupational RF-EMF exposures were estimated for study participants based on lifetime job histories linked to the RF-JEM using three different methods: (1) by considering RF-EMF intensity among all exposed jobs, (2) by considering RF-EMF intensity among jobs with an exposure prevalence ≥ the median exposure prevalence of all exposed jobs, and (3) by considering RF-EMF intensity of jobs of participants who reported RF-EMF source use. Stratified conditional logistic regression models were used, considering various lag periods and exposure time windows defined a priori. Generally, no clear associations were found for glioma or meningioma risk. However, some statistically significant positive associations were observed including in the highest exposure categories for glioma for cumulative and TWA exposure in the 1- to 4-year time window for electric fields (E) in the first JEM application method (odds ratios [ORs] = 1.36, 95% confidence interval [95% CI] 1.08, 1.72 and 1.27, 95% CI 1.01, 1.59, respectively), as well as for meningioma for cumulative exposure in the 5- to 9-year time window for electric fields (E) in the third JEM application method (OR = 2.30, 95% CI 1.11, 4.78). We did not identify convincing associations between occupational RF-EMF exposure and risk of glioma or meningioma.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.511
Threshold uncertainty score0.439

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.271
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2024
Admission routes2
Has abstractyes

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