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Record W4402808269 · doi:10.1101/2024.09.13.610754

Savings in visuomotor learning is associated with connectivity changes within a cerebello-thalamo-cortical network encoding movement errors

2024· preprint· en· W4402808269 on OpenAlexaff
Lucas Struber, Laurent Lamalle, Pierre-Alain Barraud, Aurélien Courvoisier, Rafael Laboissière, Takayuki Ito, Vincent Nougier, David J. Ostry, Fabien Cignetti

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2024
Typepreprint
Languageen
FieldNeuroscience
TopicMotor Control and Adaptation
Canadian institutionsMcGill University
FundersAgence Nationale de la Recherche
KeywordsNeuroscienceThalamusSomatosensory systemPsychologyAnterior cingulate cortexFunctional connectivityCerebellumCognition

Abstract

fetched live from OpenAlex

Savings refers to faster relearning upon re-exposure to a previously experienced movement perturbation. One theory suggests that the brain recognizes past errors and is therefore more able to learn from them. If true, there should be a modification of the neural response to errors during re-exposure to a perturbation. To test this idea, we imaged the brains of participants who underwent two sessions (1 day apart) of adaptation to a visuomotor perturbation and investigated brain responses to movement errors. The magnitude of movement error was entered into different types of GLMs to study error-related activation and co-activation (or functional connectivity). We identified a cerebello-thalamo-cortical network involved in the processing of movement errors during adaptation. We found that connectivity between regions of this network (i.e., between the cerebellum and the thalamus, and between the primary somatosensory cortex and the anterior cingulate cortex) became stronger during re-adaptation. Importantly, participants with the largest increases in connectivity strength were those who demonstrated the largest amounts of savings. These results establish a relationship between the ability of the brain to represent errors and the phenomenon of savings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.228
Teacher spread0.207 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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