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An Insight into Ethanopharmacology, Phytochemistry, and Pharmacological Properties of Genus Andrographis

2024· article· en· W4402847903 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCurrent Organic Chemistry · 2024
Typearticle
Languageen
FieldMedicine
TopicAndrographolide Research and Applications
Canadian institutionsNutrition International
Fundersnot available
KeywordsPhytochemistryChemistryGenusAndrographolideTraditional medicineBotanyOrganic chemistryBiology

Abstract

fetched live from OpenAlex

Andrographis is a member of the family Acantheceae. It contains approximately 44 accepted species. Among them, <i>Andrographis paniculata</i> has been extensively studied during the last decade. The genus contains triterpenoids as the main class of compound, along with carotenoids, flavonoids, glycosides, xanthones, phenolic compounds, and fatty acid compounds. <i>A. paniculata</i> has been reported in Ayurveda, homeopathy, naturopathy, and Siddha. Traditionally, the genus is utilized in treating diarrhea, parasitic problems, liver illness, various skin problems, fever, snake bites, cough and many more. Pharmacological activities like antioxidant, neuroprotective, anti-inflammatory, antimalarial, hepatoprotective, antibacterial antiviral, anticancer, and antidiabetic have been documented in it with scientific evidence. Various components found in this genus show broad biological opportunities for novel medicinal medicines. Andrographolide is the major chemical constituent present in almost all the species. It has been reported for various pharmacological activities, mostly for antioxidant and anticancer. The genus is widely spread among India, China, Southeast Asia, Sri Lanka, Vietnam, Thailand, and basically tropical and subtropical Asia. In India, it is found in Nallamala Hills, Andhra Pradesh, and South India. The present review has provided a critically analyzed vision of phytochemistry, traditional uses, and pharmacological applications of the genus Andrographis. The current information was collected systematically from scientific databases, including Google Scholar, PubMed, ACS Publications, SciFinder, Science Direct, and Web of Science.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.050
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.358
Teacher spread0.323 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it