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Record W4402860063 · doi:10.1183/13993003.00470-2024

Multidisciplinary management of adult patients with chylothorax: a consensus statement

2024· article· en· W4402860063 on OpenAlex
Abhinav Agrawal, Udit Chaddha, Samira Shojaee, G. Nadolski, Moïshe Liberman, Gary Lee, Najib M. Rahman, Janani Reisenauer, Mark K. Ferguson, Malcolm M. DeCamp, Erin A. Gillaspie, Eihab O. Bedawi, Brian Currie, David Feller‐Kopman, Ajinkya Desai, Kazuhiro Yasufuku, V. Bishay, Yaron Gesthalter, Horiana B. Grosu, Jeffrey Forris Beecham Chick, Robert J. Lentz, K. Kolli, Andrew Kaufman, Ravindra Mehta, Kush Desai, Heather Davis, Uzair Ghori, Fabien Maldonado

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEuropean Respiratory Journal · 2024
Typearticle
Languageen
FieldMedicine
TopicLymphatic Disorders and Treatments
Canadian institutionsUniversity of TorontoUniversity Health NetworkToronto General HospitalUniversité de Montréal
Fundersnot available
KeywordsMedicineChylothoraxDelphi methodStatement (logic)Multidisciplinary approachDelphiBest practiceMEDLINEEvidence-based medicineIntensive care medicineMedical educationMedical physicsSurgeryAlternative medicinePathologyManagement

Abstract

fetched live from OpenAlex

The management of chylothorax remains challenging given the limited evidence and significant heterogeneity in practice. In addition, there are no practical guidelines on the optimal approach to manage this complex condition. We convened an international group of 27 experts from 20 institutions across five countries and four specialties (pulmonary, interventional radiology, thoracic surgery and nutrition) with experience and expertise in managing adult patients with chylothorax. We performed a literature and internet search for reports addressing seven clinically relevant PICO (Patient, Intervention, Comparison and Outcome) questions pertaining to the management of adult patients with chylothorax. This consensus statement, consisting of best practice statements based on expert consensus addressing these seven PICO questions, was formulated by a systematic and rigorous process involving the evaluation of published evidence, augmented with provider experience. Panel members participated in the development of the final best practice statements using the modified Delphi technique. Our consensus statement aims to offer guidance in clinical decision making when managing patients with chylothorax while also identifying gaps in knowledge and informing future research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.367
Threshold uncertainty score0.380

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.280
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it