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Machine Learning-Driven Blockchain for Enhanced Drug Discovery and Development in Pharmaceutical Research

2024· article· en· W4402980259 on OpenAlexaff
V Asha, Shaik Anjimoon, Meenu Rani Verma, Atul Singla, Irfan Khan, Mohammed Ayad Alkhafaji

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldComputer Science
TopicComputational Drug Discovery Methods
Canadian institutionsHorizon College and Seminary
Fundersnot available
KeywordsBlockchainDrug discoveryComputer scienceDrug developmentPharmaceutical sciencesDrugData scienceComputer securityPharmacologyMedicineBioinformaticsBiology

Abstract

fetched live from OpenAlex

Machine learning (ML) and blockchain technologies have made huge steps forward in the pharmacy business by being used in the process of creating and discovering new medicines. Both breakthroughs were made possible by using both tools together. With the help of a blockchain design powered by machine learning, the study’s main goal is to come up with a new way to make drug research more effective and efficient. This method makes it possible to make molecules with a wide range of structure features that have the right pharmacological qualities. You can also make these molecules, improve the plans of clinical trials, and guess how drugs will interact with their targets. Technologies like generative adversarial networks, reinforcement learning methods, and deep learning algorithms have made it possible for these things to be used. If blockchain technology is used throughout the whole process of making medicines, it improves global openness, traceability, and data security. This is because it makes sure that managing data is safe. The tests show that the suggested method works better than the others when it comes to the process of finding and developing new drugs. This is better because the creation process is more precise, accurate, and efficient.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.010
Threshold uncertainty score0.032

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.009
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.003
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0100.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.083
GPT teacher head0.420
Teacher spread0.336 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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