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Record W4403054774 · doi:10.58931/cait.2021.1112

Oral Immunotherapy

2021· article· en· W4403054774 on OpenAlexaboutno aff
Douglas P. Mack

Bibliographic record

VenueCanadian allergy & immunology today. · 2021
Typearticle
Languageen
FieldImmunology and Microbiology
TopicImmunodeficiency and Autoimmune Disorders
Canadian institutionsnot available
Fundersnot available
KeywordsOral immunotherapyImmunotherapyMedicineImmunologyImmune system

Abstract

fetched live from OpenAlex

Food allergy affects approximately 7% of the Canadian population and is a lifelong diagnosis for many patients. While fatal anaphylaxis is rare, accidental exposures are common, with many accidental reactions being moderate- to-severe. The fear of severe or fatal anaphylaxis is of major concern and food allergy represents a significant burden on the life of food-allergic families. Until recently, the standard of care for food allergy management in North America included avoidance of the allergenic food and epinephrine autoinjector carriage. However, additional proactive therapeutic options are becoming increasingly more commonplace. Oral immunotherapy (OIT) has been investigated through real worl evidence and in phase II and III clinical trials. Canadian experience with OIT is increasing with the publication of guidelines to support this clinical activity. OIT is an elective, non-curative procedure which carries a risk of allergic reaction. Comprehensive and effective education for families to ensure informed consent is essential as part of the shared decision making (SDM) process and is key to successful OIT implementation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.068
Threshold uncertainty score0.226

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0680.027

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.207
Teacher spread0.199 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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