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Record W4403163014 · doi:10.1177/19322968241275701

The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors

2024· article· en· W4403163014 on OpenAlexaff
David C. Klonoff, Guido Freckmann, Stefan Pleus, Boris Kovatchev, David Kerr, Chui Tse, Chengdong Li, Michael S. D. Agus, Kathleen Dungan, Barbora Voglová Hagerf, Jan S. Krouwer, Wei-An Lee, Shivani Misra, Sang Youl Rhee, Ashutosh Sabharwal, Jane Jeffrie Seley, Viral N. Shah, Nam K. Tran, Kayo Waki, Chris Worth, Tiffany Tian, Rachel E. Aaron, Keetan Rutledge, Cindy Ho, Alessandra T. Ayers, Amanda Adler, David Ahn, Halis Kaan Aktürk, Mohammed E. Al‐Sofiani, Timothy S. Bailey, Matt Baker, Lia Bally, Raveendhara R. Bannuru, Elizabeth M Bauer, Yong Mong Bee, Julia E. Blanchette, Eda Cengiz, J. Geoffrey Chase, Kong Y. Chen, Daniel R. Cherñavvsky, Mark A. Clements, Gerard L. Coté, Ketan Dhatariya, Andjela Drincic, Niels Ejskjær, Juan Espinoza, Chiara Fabris, G. Alexander Fleming, Mônica Andrade Lima Gabbay, Rodolfo J. Galindo, Ana María Gómez Medina, Lutz Heinemann, Norbert Hermanns, Thanh D. Hoang, Sufyan Hussain, Peter G. Jacobs, Johan Jendle, Shashank Joshi, Suneil K. Koliwad, Rayhan Lal, Lawrence A. Leiter, Marcus Lind, Julia K. Mader, Alberto Maran, Umesh Masharani, Nestoras Mathioudakis, Michael J. McShane, Chhavi Mehta, Sun Joon Moon, James H. Nichols, David N. O’Neal, Francisco J. Pasquel, Anne L. Peters, Andreas Pfützner, Rodica Pop‐Busui, Pratistha Ranjitkar, Connie M. Rhee, David B. Sacks, Signe Schmidt, Simon M. Schwaighofer, Bin Sheng, Gregg D. Simonson, Koji Sode, Elias K. Spanakis, Nicole L. Spartano, Guillermo E. Umpierrez, Maryam Vareth, Hubert W. Vesper, Jing Wang, Eugene E. Wright, Alan H.B. Wu, Sewagegn Yeshiwas, Mihail Zilbermint, Michael A. Kohn

Bibliographic record

VenueJournal of Diabetes Science and Technology · 2024
Typearticle
Languageen
FieldMedicine
TopicHyperglycemia and glycemic control in critically ill and hospitalized patients
Canadian institutionsUniversity of TorontoSt. Michael's Hospital
FundersMannKind CorporationUniversity of California, DavisCenters for Disease Control and PreventionRoche Diabetes CareSanofiNational Institute of Diabetes and Digestive and Kidney DiseasesNIHR Imperial Biomedical Research CentreCardinal HealthTandem Diabetes CareNovo NordiskNational Institute for Health and Care ResearchDexcomInsulet CorporationWellcome TrustU.S. Department of DefenseEli Lilly and CompanyAgency for Toxic Substances and Disease RegistryAstraZenecaNovo Nordisk FondenNational Center for Advancing Translational SciencesLeona M. and Harry B. Helmsley Charitable TrustU.S. Department of Veterans AffairsU.S. Department of Health and Human ServicesAbbott Diabetes CareNational Science Foundation
KeywordsDiabetes mellitusContinuous glucose monitoringBlood Glucose Self-MonitoringGridComputer scienceMedicineData scienceType 1 diabetesEndocrinologyMathematics

Abstract

fetched live from OpenAlex

INTRODUCTION: An error grid compares measured versus reference glucose concentrations to assign clinical risk values to observed errors. Widely used error grids for blood glucose monitors (BGMs) have limited value because they do not also reflect clinical accuracy of continuous glucose monitors (CGMs). METHODS: Diabetes Technology Society (DTS) convened 89 international experts in glucose monitoring to (1) smooth the borders of the Surveillance Error Grid (SEG) zones and create a user-friendly tool-the DTS Error Grid; (2) define five risk zones of clinical point accuracy (A-E) to be identical for BGMs and CGMs; (3) determine a relationship between DTS Error Grid percent in Zone A and mean absolute relative difference (MARD) from analyzing 22 BGM and nine CGM accuracy studies; and (4) create trend risk categories (1-5) for CGM trend accuracy. RESULTS: The DTS Error Grid for point accuracy contains five risk zones (A-E) with straight-line borders that can be applied to both BGM and CGM accuracy data. In a data set combining point accuracy data from 18 BGMs, 2.6% of total data pairs equally moved from Zones A to B and vice versa (SEG compared with DTS Error Grid). For every 1% increase in percent data in Zone A, the MARD decreased by approximately 0.33%. We also created a DTS Trend Accuracy Matrix with five trend risk categories (1-5) for CGM-reported trend indicators compared with reference trends calculated from reference glucose. CONCLUSION: The DTS Error Grid combines contemporary clinician input regarding clinical point accuracy for BGMs and CGMs. The DTS Trend Accuracy Matrix assesses accuracy of CGM trend indicators.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.047
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.012
Threshold uncertainty score0.045

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.047
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0060.006
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.308
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations37
Published2024
Admission routes1
Has abstractyes

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