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Record W4403233332 · doi:10.3892/mi.2024.196

Neurological and systemic effects of cocaine toxicity: A case report and review of the literature

2024· article· en· W4403233332 on OpenAlexaff
Zachary M. Hong, Julie Kromm

Bibliographic record

VenueMedicine International · 2024
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicForensic Toxicology and Drug Analysis
Canadian institutionsFoothills Medical CentreUniversity of Calgary
Fundersnot available
KeywordsToxicityMedicineInternal medicine

Abstract

fetched live from OpenAlex

While historically utilized as a topical anesthetic and active ingredient in a variety of tonics, beverages and cure-alls, cocaine is a commonly abused illicit substance. Cocaine use is associated with a variety of neurological and systemic complications. The present study describes the case of a 23-year-old female patient presenting with profound neurological and systemic complications of cocaine, including coma, leukoencephaloapthy, neurogenic stunned myocardium, transaminitis, acute kidney injury, rhabdomyolysis and mononeuropathy. The supportive management and subsequent outcomes of the patients are discussed in detail. The approach to coma is also discussed, including stabilization and supportive care, diagnostic considerations and management. Key considerations relating prognosticating disorders of consciousness are also highlighted.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.007
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0070.006
Science and technology studies0.0020.002
Scholarly communication0.0020.003
Open science0.0020.002
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.399
Teacher spread0.371 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes1
Has abstractyes

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