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Evaluation of linear scars revision with and without platelet-rich fibrin and autologous unprocessed bone marrow injection

2024· article· en· W4403357092 on OpenAlexaboutno aff
Ashraf Hussein, Osama Antar, Mohamed Elyamany

Bibliographic record

VenueThe Egyptian Journal of Surgery · 2024
Typearticle
Languageen
FieldMedicine
TopicPeriodontal Regeneration and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsScarsPlatelet-rich fibrinMedicineFibrinSurgeryPlateletBone marrowPathologyInternal medicineImmunology

Abstract

fetched live from OpenAlex

Introduction: There are many modalities of traditional methods of linear scar treatment including derma abrasion,chemical ablation, laser therapy, and use of surgical excision and grafting. However, surgical treatments, with or withoutsupplementary nonsurgical treatments offers a confusing picture of widely variable ‘success’ rates, recurrence rates,patient populations, and follow-up periods.Aim: Our main objective was to improve the results of treatment of linear scars. Also to evaluate of the results of addingplatelet-rich fibrin (PRF) and autologous unprocessed bone marrow in surgically revised linear scars.Patients and Methods: Total study number of 16 patients (nine men, seven women), aged 22–52 years were enrolled inthis study. Six patients had the scar in the abdomen, four patients had the scar in the forearm, three in the leg and threein the neck. Assessment of scar was done including history, clinical examination using Vancouver Scar Scale, patient’and doctor’ scar satisfaction. All patients were treated with scar revision by injecting half of the wound with the aspiratedautologous unprocessed bone marrow and PRF. On follow-up, the patients were photographed at the start of the study(preoperative), weekly for first 2 weeks (postoperative), and monthly for the next 6 months.Results: Adding heparinized autologous unprocessed bone marrow and PRF; may improve the pattern of scar revision.This preliminary work suggests that there were differences in the time of healing, scar appearance (100%) as P value was0.021, pliability, height (62.5%) a P value was (0.009), vascularity and satisfaction (43.8%) between both groups of thestudy.Conclusion: This novel treatment appeared to be safe and effective for scar treatment. To illustrate significant statisticaldifferences, we need a larger sampling and longer follow-up periods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.313
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2024
Admission routes1
Has abstractyes

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