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Record W4403619103 · doi:10.1002/cjce.25717

Biorecycling of polylactide: From enzymatic depolymerization to biotransformation of released products

2025· article· en· W4403619103 on OpenAlexvenueno aff
Alaric Catard, Isabelle Chevalot, Sandrine Hoppe

Bibliographic record

VenueThe Canadian Journal of Chemical Engineering · 2025
Typearticle
Languageen
FieldMaterials Science
Topicbiodegradable polymer synthesis and properties
Canadian institutionsnot available
Fundersnot available
KeywordsDepolymerizationBiotransformationChemistryEnzymeOrganic chemistryBiochemistry

Abstract

fetched live from OpenAlex

Abstract Polylactic acid (PLA) is a polymer that can replace several petroleum‐based polymers due to its properties and bio‐sourced nature. However, sustainable recycling processes of PLA avoiding the creation of waste and enabling it to be used as a raw material must be implemented. Enzymatic hydrolysis seems to be a promising way to recycle PLA. The different approaches that have led to the discovery of new PLA depolymerizing enzymes are reviewed here. Moreover, an overview of the various factors affecting enzymatic depolymerization of PLA have been done as well as the contribution of enzyme engineering in understanding the essential residues of these enzymes and improving their properties (e.g., thermostability and activity). Finally, enzymatic polymerization and biosynthesis of PLA from lactide or lactic acid have been reviewed to provide an overview of the various biotechnological approaches that could enable PLA to be completely recycled and remade.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.189
Teacher spread0.179 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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