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Record W4403774784 · doi:10.26717/bjstr.2024.58.009220

Antimicrobial Efficacy of a 200 ppm Hypochlorous Acid Solution for Ocular Hygiene: In Vitro Analysis Against Microorganisms Linked to Ocular Infections and Dry Eye Disease

2024· article· en· W4403774784 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueBiomedical Journal of Scientific & Technical Research · 2024
Typearticle
Languageen
FieldMedicine
TopicMedical and Biological Ozone Research
Canadian institutionsnot available
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsHypochlorous acidAntimicrobialMicrobiologyMicroorganismIn vitroDiseaseMedicineChemistryBacteriaBiologyPathologyBiochemistry

Abstract

fetched live from OpenAlex

This study investigates the in vitro antimicrobial efficacy of a 200 ppm hypochlorous acid (HOCl) solution (I-LID ‘N LASH HOCl CLEANSING SPRAY from I-MED Pharma Inc.), targeting microorganisms associated with ocular infections and dry eye disease. Using Colony-forming Unit (CFU) and bacteriophage plaque reduction bioassays, the study evaluates the impact of different HOCl concentrations on Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Candida albicans, Aspergillus flavus, Fusarium oxysporum and the <i>Lambda</i> phage virus.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.011
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.531
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0100.011
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.007
Science and technology studies0.0000.003
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.391
Teacher spread0.343 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it