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Record W4403835891 · doi:10.7759/cureus.72538

Coral Crisis: Palytoxin-Induced Keratoconjunctivitis in Marine Experts

2024· article· en· W4403835891 on OpenAlexaff
Nikolas P Foresteire, Luis Cabrera, Cory Howard, Alexandra Craen, Ori Gat

Bibliographic record

VenueCureus · 2024
Typearticle
Languageen
FieldEnvironmental Science
TopicMarine Toxins and Detection Methods
Canadian institutionsBrandon University
Fundersnot available
KeywordsPalytoxinMedicineCoralMarine toxinOceanography

Abstract

fetched live from OpenAlex

Palytoxin (PTX or PLTX), a potent and rare marine toxin derived from certain coral species, poses significant risks to human health upon exposure, including the development of acute respiratory distress syndrome. We present a case report detailing the experiences of two expert marine biologists who inadvertently came into contact with palytoxin while handling marine organisms in a controlled environment. Shortly after exposure, both biologists developed severe keratoconjunctivitis, characterized by acute inflammation of the conjunctiva and cornea. Clinical manifestations included intense ocular pain, photophobia, conjunctival injection, and corneal epithelial defects, with symptoms progressing rapidly post exposure. Initial management involved immediate irrigation with a saline solution, followed by topical corticosteroids and lubricants to alleviate inflammation and promote corneal healing. Both individuals responded favorably to treatment, with resolution of symptoms within several days. This report underscores the importance of stringent adherence to safety protocols and awareness among marine biologists regarding the risks associated with palytoxin exposure, emphasizing the need for prompt recognition and appropriate management of ocular manifestations to minimize potential long-term sequelae.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.769
Threshold uncertainty score0.986

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0150.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.292
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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