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Record W4403850656 · doi:10.7759/cureus.72613

Role of Neurosurgical Interventions in the Treatment of Movement Disorders Like Parkinson’s Disease, Dystonia, and Tourette Syndrome

2024· review· en· W4403850656 on OpenAlexaff
Anishka Chourey, Yasmin Kabir, Héctor Daniel García Mata, Erika Tiepolo, Ivana Lizeth Fiallos Vinueza, Cara Mohammed, Abrar Ahmed Thottakurichi

Bibliographic record

VenueCureus · 2024
Typereview
Languageen
FieldMedicine
TopicNeurological disorders and treatments
Canadian institutionsTrinity College
Fundersnot available
KeywordsMedicineDystoniaTourette syndromeMovement disordersTicsParkinson's diseaseDeep brain stimulationEssential tremorPhysical medicine and rehabilitationDyskinesiaDiseasePsychiatryPediatricsInternal medicine

Abstract

fetched live from OpenAlex

This article provides an overview of neurosurgical therapies for movement disorders (MDs), including Tourette syndrome, dystonia, Parkinson's disease (PD), and others. It focuses on the benefits of these treatments and suggests directions for further research. A total of 10 years' worth of English-language PubMed articles were combed through, with an emphasis on studies conducted in North America. To manage MDs like Parkinson's disease and Tourette syndrome, the results suggest that non-invasive neuromodulation techniques, closed-loop deep brain stimulation (DBS), and other advanced therapies may become the treatment of choice in the future. Research on dystonia is being focused on improving treatment methods by investigating new areas of the brain that might be stimulated through neurosurgery and looking at gene therapy. Modern technological developments, such as non-invasive neuromodulation procedures and improved imaging, provide promising substitutes for traditional surgical approaches. This study highlights the need for continuous clinical trials for better outcomes, which is why research and development in this area must continue.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.004
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0040.003
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.336
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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