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Record W4404033081 · doi:10.1016/j.gaceta.2024.102424

Unequal impact of COVID-19 on excess deaths, life expectancy, and premature mortality in Spanish regions (2020-2021)

2024· article· en· W4404033081 on OpenAlexaff
Nazrul Islam, Fernando García López, Miguel Ángel Royo‐Bordonada, Kamlesh Khunti, Sarah Lewington, Ben Lacey, Martin White, Eva Morris, Marı́a Victoria Zunzunegui

Bibliographic record

VenueGaceta Sanitaria · 2024
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 and healthcare impacts
Canadian institutionsUniversité de Montréal
FundersEconomic and Social Research CouncilNational Institute for Health and Care ResearchMedical Research CouncilCenters for Disease Control and Prevention FoundationCancer Research UKBritish Heart FoundationWellcome TrustAmgen
KeywordsCoronavirus disease 2019 (COVID-19)Life expectancy2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PandemicExcess mortalityBetacoronavirusDemographyMEDLINEMedicineVirologyMortality rateEnvironmental healthBiologyPopulationOutbreakInternal medicineDisease

Abstract

fetched live from OpenAlex

We aimed to estimate regional inequalities in excess deaths and premature mortality in Spain during 2020 and 2021, before high vaccination coverage against COVID-19. With data from the National Institute of Statistics, within each region, sex, and age group, we estimated the excess deaths, the change in life expectancy at birth ( e 0 ) and age 65 ( e 65 ) and years of life lost as the difference between the observed and expected deaths using a time series analysis of 2015-2019 data and life expectancies based on Lee-Carter forecasting using 2010-2019 data. From January 2020 to June 2021, an estimated 89,200 (men: 48,000; women: 41,200) excess deaths occurred in Spain with a substantial regional variability (highest in Madrid: 22,000, lowest in Canary Islands: −210). The highest reductions in e 0 in 2020 were observed in Madrid (men −3.58 years, women −2.25), Castile-La Mancha (−2.72, −2.38), and Castile and Leon (−2.13, −1.39). During the first half of 2021, the highest reduction in e 0 was observed in Madrid for men (−2.09; −2.37 to −1.84) and Valencian Community for women (−1.63; −1.97 to −1.3). The highest excess years of life lost in 2020 was in Castile-La Mancha (men: 5370; women: 3600, per 100 000). We observed large differences between reported COVID-19 deaths and estimated excess deaths across the Spanish regions. Regions performed highly unequally on excess deaths, life expectancy and years of life lost. The investigation of the root causes of these regional inequalities might inform future pandemic policy in Spain and elsewhere. Estimar las desigualdades regionales en exceso de muertes y mortalidad prematura en España entre enero de 2020 y junio de 2021, antes de la vacunación poblacional masiva contra la COVID-19. Con datos del Instituto Nacional de Estadística se estimaron el exceso de muertes con respecto a las muertes esperadas por regione, sexo y grupos de edad, el cambio en la esperanza de vida al nacer ( e 0 ) y a los 65 años ( e 65 ), y los años de vida perdidos, mediante series temporales (2015-2019) y el pronóstico de Lee-Carter (2010-2019). En el periodo del estudio, el exceso de muertes fue de 89.200 (hombres 48.000, mujeres 41.200), con una gran variabilidad regional (desde Madrid con 22.000 hasta las Islas Canarias con −210). Las mayores reducciones de e 0 en 2020 fueron en Madrid (hombres −3,58 años, mujeres −2,25), Castilla-La Mancha (−2,72, −2,38) y Castilla y León (−2,13, −1,39), y en el primer semestre de 2021 fueron en Madrid (hombres −2,09; −2,37 a −1,84) y en la Comunidad Valenciana (mujeres −1,63; −1,97 a −1,3). El mayor exceso de años de vida perdidos en 2020 se produjo en Castilla-La Mancha (hombres 5370, mujeres 3600, por 100.000). Hubo grandes diferencias entre las muertes por COVID-19 notificadas y el exceso de muertes. Se observaron enormes desigualdades regionales en el exceso de muertes, la esperanza de vida y los años de vida perdidos. La determinación de las causas fundamentales de estas desigualdades podría servir para mejorar las políticas de salud pública en pandemias futuras.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.113
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.074
GPT teacher head0.421
Teacher spread0.347 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations2
Published2024
Admission routes1
Has abstractyes

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