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Record W4404042681 · doi:10.1039/d4em00513a

Validation of a laboratory spray generation system and its use in a comparative study of hexamethylene diisocyanate (HDI) evaluation methods

2024· article· en· W4404042681 on OpenAlexafffund
Hugues Ahientio, Loïc Wingert, Sébastien Gagné, Livain Breau, Jacques Lesage, Simon Aubin

Bibliographic record

VenueEnvironmental Science Processes & Impacts · 2024
Typearticle
Languageen
FieldMedicine
TopicOccupational exposure and asthma
Canadian institutionsInstitut de recherche Robert-Sauvé en santé et en sécurité du travailUniversité du Québec à Montréal
FundersInstitut de Recherche Robert-Sauvé en Santé et en Sécurité du Travail
KeywordsHexamethylene diisocyanateReactivity (psychology)EngineeringEnvironmental scienceForensic engineeringChemistryPolyurethaneOrganic chemistryMedicinePathology

Abstract

fetched live from OpenAlex

, respectively, with spatial homogeneity (RSD) of 5.8% and 16.5%. The particle-size distribution (MMAD) of 4 μm was measured using a cascade impactor and an electrical low-pressure impactor. The samples generated were used to correlate the amount of isocyanates collected with scanning electron microscope images of droplets on a filter. Three methods were compared to the reference method-an impinger with a backup glass fibre filter (GFF) and 1,2-methoxyphenylpiperazine (MP) based on ISO 16702/MDHS 25-in six generation experiments: (1) Swinnex cassette 13 mm GFF MP (MP-Swin); (2) closed-face cassette 37 mm GFF (end filter and inner walls) MP (MP-37); and (3) denuder and GFF dibutylamine (DBA) (ISO 17334-1 Asset). The analysis revealed clear trends regarding which sampler sections collected HDI (mainly in the vapor phase) or isocyanurate (exclusively in the particulate phase). The study found no significant bias between the tested methods (MP-Swin, MP-37, and Asset) and the reference method (impinger) for both HDI monomer and isocyanurate. The three tested methods showed limits of agreement beyond the acceptable range of ±30% (95% confidence interval), largely due to data variability, though MP-Swin and MP-37 exhibited lower variability than Asset. The results will be further evaluated in a real-world environment where similar clear coats are used.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.169
Threshold uncertainty score0.347

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.072
GPT teacher head0.397
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes2
Has abstractyes

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