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Record W4404065708 · doi:10.1101/2024.11.05.24316739

LONG TERM NEUROPSYCHOLOGICAL OUTCOME AND EFFECT OF COGNITIVE RESERVE IN RETIRED ATHLETES

2024· preprint· en· W4404065708 on OpenAlexaff
Bonnie Kate Dewar, James Murray, Hugo Pedder, Michael S. Turner

Bibliographic record

VenuemedRxiv · 2024
Typepreprint
Languageen
FieldMedicine
TopicOphthalmology and Visual Health Research
Canadian institutionsTraffic Injury Research Foundation
Fundersnot available
KeywordsNeuropsychologyTerm (time)AthletesOutcome (game theory)Cognitive reserveCognitionPsychologyPhysical medicine and rehabilitationMedicineCognitive impairmentPhysical therapyEconomicsPsychiatryPhysics

Abstract

fetched live from OpenAlex

ABSTRACT Objectives Cognitive reserve is hypothesised as a protective process against cognitive impairment arising from brain injury. Different life experiences provide a shield against the effects of brain changes to modulate or delay the expression of cognitive impairment. The current study investigated the long-term neuropsychological outcome of retired, predominantly equestrian, athletes. Methods Neuropsychological performance of participants with a history of concussion was compared to age-matched controls using Principle Components Analysis (PCA) regression, adjusted for participant characteristics. Premorbid function was used as an index of cognitive reserve. Results Three components were identified that explained greater than 95 percent of the variance in 14 neuropsychology tests; the first component (PC1) explained 87 percent of the variance. A regression model on PC1 identified an association between concussion and PC1, with lower scores in concussed participants with lower premorbid function. Conclusions A history of concussion is associated with lower neuropsychological performance, and this is more pronounced in individuals with lower premorbid functioning, an indicator of cognitive reserve. What is already known on this topic There is a need to clarify long term neuropsychological outcome following sports related concussion. What this study adds There is a subset of retired athletes who are better able to withstand the cognitive impact of sports related concussion given higher cognitive reserve. How this study might affect research, practice or policy Future research needs to explore modifiable factors to protect brain health in retired athletes, with the use of clinically meaningful measures of cognitive functioning. There is a need for longitudinal assessment and follow-up to clarify the role of cognitive reserve in retired athletes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.179
GPT teacher head0.528
Teacher spread0.349 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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