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Fertility following successful treatment of canine pyometra

2024· article· en· W4404073838 on OpenAlexaboutno aff
Gopinatha Arjun, Manali Sandesh Patil, S. Kantharaj, K. Kalidasa Murugavel, H Hemalatha

Bibliographic record

VenueInternational Journal of Advanced Biochemistry Research · 2024
Typearticle
Languageen
FieldVeterinary
TopicVeterinary Medicine and Surgery
Canadian institutionsnot available
Fundersnot available
KeywordsPyometraFertilityMedicineInternal medicineEnvironmental healthUterusPopulation

Abstract

fetched live from OpenAlex

Canine pyometra is a potentially life-threatening condition characterized by pus accumulation in the uterus, often triggered by hormonal changes during the estrous cycle. It commonly affects intact female dogs over five years old due to prolonged progesterone exposure post-estrus during each estrous cycle. The present study discusses the fertility outcome of a six-year-old female Labrador Retriever treated for open cervix pyometra. The dog was presented to the Veterinary Clinical Complex, RIVER, Puducherry, with foul-smelling mucopurulent vulvar discharge for a week. The dog had whelped four times, with the last pregnancy ending in abortion, and had shown proestral bleeding two and a half months earlier. Clinical examination revealed a distended abdomen, inappetence, dullness and purulent discharge from vulva. Ultrasonography showed anechoic sacculations in the uterus, and haematology indicated severe leucocytosis, monocytosis, thrombocytopenia, and elevated creatinine. Based on the clinical, haematological and ultrasonographic examinations, the case was diagnosed as open cervix pyometra. The dog was treated with Tab. Mifepristone (5 mg/kg for 3 days) orally and per-vaginal misoprostol (3 mcg/kg) until uterine evacuation, alongside intravenous ceftriaxone-tazobactam (30 mg/kg) for 14 days and supportive fluids for 7 days. Probiotics (Tab. Renodis- One tablet a day PO) was prescribed for 10 days. Seven days after the treatment, ultrasonography revealed a significant reduction in uterine size, the animal regained feed intake indicating full recovery. The dog was followed another 6 months. It showed proestral bleeding 4 months after treatment, became pregnant and delivered 5 healthy puppies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.142
GPT teacher head0.489
Teacher spread0.347 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2024
Admission routes1
Has abstractyes

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