MétaCan
Menu
Back to cohort
Record W4404077146 · doi:10.1016/j.advnut.2024.100335

Are Lean Body Mass and Fat-Free Mass the Same or Different Body Components? A Critical Perspective

2024· review· en· W4404077146 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueAdvances in Nutrition · 2024
Typereview
Languageen
FieldMedicine
TopicBody Composition Measurement Techniques
Canadian institutionsUniversity of Alberta
FundersNational Institute of Diabetes and Digestive and Kidney DiseasesNutrition Obesity Research Center, University of North CarolinaNational Institutes of HealthCanada Research Chairs
KeywordsLean body massPerspective (graphical)Fat free massCritical mass (sociodynamics)Fat massBody mass indexMedicineBody weightEndocrinologySociologyComputer science

Abstract

fetched live from OpenAlex

The 2-component molecular-level model dividing body mass into fat and fat-free mass (FFM) is a cornerstone of contemporary body composition research across multiple disciplines. Confusion prevails, however, as the term lean body mass (LBM) is frequently used interchangeably with FFM in scientific discourse. Are LBM and FFM the same or different body components? Captain Albert R. Behnke originated the LBM concept in 1942 and he argued that his "physiological" LBM component included "essential" fat or structural lipids whereas FFM is a chemical entity "free" of fat. Classical experimental animal and human studies conducted during Behnke's era laid the foundation for the widely used body density and total body water 2-component molecular-level body composition models. Refined body composition models, organization of lipids into structural and functional groupings, and lipid extraction methods all have advanced since Behnke's era. Our review provides an in-depth analysis of these developments with the aim of clarifying distinctions between the chemical composition of LBM and FFM. Our retrospective analysis reveals that FFM, derived experimentally as the difference between body weight and extracted neutral or nonpolar lipids (mainly triglycerides), includes polar or structural lipids (that is, Behnke's "essential" fat). Accordingly, LBM as originally proposed by Behnke has the same chemical composition as FFM, thus answering a longstanding ambiguity in the body composition literature. Bringing body composition science into the modern era mandates the use of the chemically correct term FFM with the elimination of the duplicative term LBM that today has value primarily in a historical context. Avoiding the use of the term LBM additionally limits confusion surrounding similar widely used body composition terms such as lean mass, lean soft tissue mass, and lean muscle mass.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.699
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.066
GPT teacher head0.400
Teacher spread0.333 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it