MétaCan
Menu
Back to cohort
Record W4404534236 · doi:10.1039/d4dd00197d

Quantitative analysis of miniature synaptic calcium transients using positive unlabeled deep learning

2024· article· en· W4404534236 on OpenAlexafffund
Frederic Beaupré, Anthony Bilodeau, Theresa Wiesner, G. LECLERC, Mado Lemieux, Gabriel Nadeau, Katrine Castonguay, Bi Fan, Simon Labrecque, Renée Hložek, Paul De Koninck, Christian Gagné, Flavie Lavoie‐Cardinal

Bibliographic record

VenueDigital Discovery · 2024
Typearticle
Languageen
FieldEngineering
TopicAdvanced Memory and Neural Computing
Canadian institutionsMila - Quebec Artificial Intelligence InstituteCanadian Institute for Advanced ResearchUniversity of TorontoCanadian Institute for Theoretical AstrophysicsUniversité Laval
FundersNext Generation Network for NeuroscienceFonds de recherche du Québec – Nature et technologiesFonds de Recherche du Québec - SantéNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health ResearchCanada Research ChairsCanada Research Coordinating CommitteeCanadian Institute for Advanced ResearchConnaught FundNational Science Foundation
KeywordsCalciumNeuroscienceArtificial intelligenceDeep learningPattern recognition (psychology)Computer sciencePsychologyMedicineInternal medicine

Abstract

fetched live from OpenAlex

We developed a positive unlabeled deep learning scheme for detection and segmentation of miniature synaptic calcium transients. Combining deep learning and feature analysis, it measures the impact of cLTP on transient morphology and dynamics.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.275
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes2
Has abstractyes

Explore more

Same venueDigital DiscoverySame topicAdvanced Memory and Neural ComputingFrench-language works237,207