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Record W4404868580 · doi:10.5376/bm.2024.15.0025

Comprehensive Genomic Analysis of <i>Atractylodes macrocephala</i>: Unveiling Its Medicinal Functions and Genetic Secrets

2024· article· en· W4404868580 on OpenAlexvenueno aff
Xichen Wang, Huixian Li, Chuchu Liu

Bibliographic record

VenueBioscience Methods · 2024
Typearticle
Languageen
FieldMedicine
TopicTraditional Chinese Medicine Analysis
Canadian institutionsnot available
Fundersnot available
KeywordsAtractylodesTraditional medicineBiologyGeneticsMedicineAlternative medicine

Abstract

fetched live from OpenAlex

Atractylodes macrocephala is a key herb in traditional medicine with diverse medicinal properties. This study provides an overview of its botanical, phytochemical, pharmacological, and genomic aspects, highlighting its potential in modern medicine and agriculture. The study covers the morphological characteristics, geographic distribution, and cultivation techniques of A. macrocephala . It details the phytochemical composition, methods of analysis, and biological activities. Traditional medicinal uses and pharmacological activities such as antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, and antiviral properties are discussed. Genomic analysis includes genome sequencing, functional gene annotation, and comparative genomics. The genetic basis of medicinal properties, including key genes and pathways, phytochemical biosynthesis, and pharmacological activities, is examined. Biotechnological applications like genetic engineering, breeding, conservation, and synthetic biology are also studyed. This study consolidates knowledge on A. macrocephala , emphasizing its traditional and modern applications. Future research should address knowledge gaps, leverage emerging technologies, and integrate genomic data with traditional knowledge to enhance its medicinal and agricultural use.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.369
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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