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Record W4404877316 · doi:10.1002/047084289x.rn02514

Thionyl Fluoride

2024· other· en· W4404877316 on OpenAlexaff
Lauriane C. Peyrical

Bibliographic record

VenueEncyclopedia of Reagents for Organic Synthesis · 2024
Typeother
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicFluorine in Organic Chemistry
Canadian institutionsUniversité de Montréal
Fundersnot available
KeywordsChemistry

Abstract

fetched live from OpenAlex

image [7783‐42‐8] SOF 2 (MW 86.061) InChI = 1S/F2OS/c1‐4(2)3 InChIKey = LSJNBGSOIVSBBR‐UHFFFAOYSA‐N (reagent used for fluorination, nucleophilic acyl substitutions including one‐pot peptide coupling and introduction of S(O)F group) Alternative Names: sulfinyl fluoride, sulfur difluoride oxide, sulfur difluoride monoxide, sulfurous oxyfluoride, thionyl difluoride. Physical Data: mp −129.5 °C, bp −43.8 °C, d 1.758 g cm −3 . Solubility: soluble in ethanol, ether, and benzene. Hydrolyzes in water. Form Supplied in: colorless gas packaged in cylinders, commercially available. Analysis of Reagent Purity: singlet in 19 F NMR at δ −72.2. 1,2 IR (cm −l ) 1333, 808, 748, 530, 410, 390. 3 Preparative Methods: thionyl fluoride is typically generated from thionyl chloride and a fluoride salt followed by condensation of the resulting gas. 4 More conveniently, it can be generated ex situ, bubbled in various organic solvents, and used directly or kept as a stock solution. 5 It is also one of the major decomposition products of sulfur hexafluoride under electric discharges, by hydrolysis of sulfur tetrafluoride in air. 6 Purification: fractionated distillation through a low‐temperature column. Handling, Storage, and Precautions: toxic gas that should be handled in a well‐ventilated fume hood.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.146
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.1040.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.388
Teacher spread0.336 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueEncyclopedia of Reagents for Organic SynthesisSame topicFluorine in Organic ChemistryFrench-language works237,207