Assessment of Clinical Outcome Based on Womac Score Between Intra-Articular Injection of Platelet Rich Plasma and Long Acting Corticosteriod in Stage Ii-Iii Kelgren-Lawrence Osteoarthritis of Knee
Bibliographic record
Abstract
Introduction: Osteoarthritis is chronic degenerative condition of joint characterized by progressive deterioration of cartilage and inflammation, causing pain and limiting functional of joints. Intra-articular corticosteroid injections are most commonly used to reduce the symptoms in Osteoarthritis, but their effects are often last for short-term and may come with risks factors. Platelet-rich plasma (PRP), an autologous treatment, has evolved into a potential alternative method to improve the limitation of joint function that may provide more sustainable relief. Objective: This study is to determine clinical outcomes of intra-articular injections of platelet-rich plasma and steroids for the treatment of knee osteoarthritis over a period of 6 months follow-up. The focus of this study is to measuring the extent of pain relief and functional improvement. Methods: A prospective randomized control study was conducted in 50 patients diagnosed with Grade II and III knee OA. Patients allocated randomly into two groups: Group A (corticosteroid injection) and Group B (PRP injection). All the patients had undergone a Clinical examination and then outcome were assessed using Visual Analogue Scale (VAS) for pain and Western Ontario and McMaster Universities Arthritis Index (WOMAC) for function at baseline, 1, 3, and 6 months. Results: Both modality of treatment showed improvements in pain and function, with PRP showed a better reduction of VAS and WOMAC scores. At end of 6 months, VAS score in Group A decreased by 2.5 points, while Group B showed reduction of only 4.2-point. WOMAC total scores in Group B improved more significantly reduction in pain, stiffness, and function improvement compared to Group A. Conclusion: In our study both corticosteroid and platelet rich plasma showed significant reduction in pain and improving function of KL grade II & III osteoarthritis knee. Intra-articular PRP injection showed significant short-term similar reduction of pain but knee function with no significant difference when compared to corticosteroids therapy at end of follow-up. However, PRP treatment resulted in a longer sustained effect. Intra-articular PRP injection is safe, it can reduce pain, and it can improve knee function of patients with mild/moderate knee OA for longer period. DOI: https://doi.org/10.52783/jchr.v14.i6.6870
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".