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Record W4405092600 · doi:10.1182/blood-2024-202435

Patient Decision Aid for Extended Duration Thromboprophylaxis for Major Abdominopelvic Cancer Surgery: A Usability Study

2024· article· en· W4405092600 on OpenAlexaffabout
Abdelrahman Noureldin, Victoria Ivankovic, Mary Farnand, Celine Dainhi, Rebecca C. Auer, Sameer Apte, Lev Bubis, Pamela Hebbard, Justin Rivard, Megan Delisle, Marc Carrier

Bibliographic record

VenueBlood · 2024
Typearticle
Languageen
FieldMedicine
TopicVenous Thromboembolism Diagnosis and Management
Canadian institutionsOttawa HospitalUniversity of ManitobaCancerCare ManitobaUniversity of Ottawa
Fundersnot available
KeywordsMedicineUsabilitySurgeryCancerDuration (music)General surgeryInternal medicineComputer scienceHuman–computer interaction

Abstract

fetched live from OpenAlex

Background: Clinical guidelines recommend patients receive extended duration thromboprophylaxis for 30 days following major abdominopelvic cancer surgery. There is equipoise regarding this recommendation amongst providers and patients. We developed a risk-stratified patient decision aid (PtDA) for patients undergoing major abdominopelvic cancer surgery considering extended duration thromboprophylaxis. We previously demonstrated the PtDA was acceptable to patients and clinicians and enhanced decision-making quality. However, the PtDA made was difficult to use in the perioperative setting. The objective of this study was to evaluate and improve the usability of the PtDA in the perioperative setting. Methods: We used an iterative process guided by a user-centered design framework. Consecutive patients undergoing major abdominopelvic cancer surgery from two major cancer centers in Canada, The Ottawa Hospital Cancer Center (TOHCC) and CancerCare Manitoba (CCMB), were recruited. Healthcare professionals involved in discharging patients who completed the PtDA were also recruited. Recruitment rate was defined as the number of total patients approached divided by the total eligible patients who consented to be contacted. Eligible and consented patients were invited to complete the PtDA and the Post Study System Usability Questionnaire (PSSUQ), and to record their decision regarding extended duration thromboprophylaxis. Adherence rate was defined as the number of eligible patients thereafter who actually completed the PSSUQ. Usability was also assessed by healthcare professionals discharging patients using the Consolidated Framework for Implementation Research (CFIR) Barrier Buster Tool. Results: Across both sites patients were recruited from November 2023 until May 2024. 108 consecutive patients were approached with study details, 22 refused to be contacted and 7 were ineligible The recruitment rate was 73% (79/108). Of the eligible and consented patients, the adherence rate was 25% (20/79). Overall, 15 patients from TOHCC and 5 from CCMB used the PtDA to help their decision regarding extended duration thromboprophylaxis. Eight (40%) patients were males, and 12 (60%) were females. Out of the 20 patients who used the PtDA, 18 (90%) completed the PSSUQ and reported their decision regarding extended duration thromboprophylaxis: 13 (65%) patients made a decision using our PtDA compared to 5 (25%) who preferred not to decide. Among the 13 who made a decision, 7 (54%) decided not to take extended duration thromboprophylaxis and 6 (46%) decided to take extended duration thromboprophylaxis. Regarding usability, the overall median score was 2 (range 2 - 6) on the PSSUQ. The usefulness subdomain median score was 3 (range 2 - 7). The median quality of information subdomain score was 2 (1 - 7). The median quality of design score was 2 (1 - 7). A total of 15 healthcare professionals were involved in discharging patients who used the PtDA and completed the PSSUQ. All healthcare professionals were resident physicians. Eight (53%) were males and seven (47%) were females. All 15 (100%) completed the follow-up CFIR Tool. From the 12 factors evaluated in the CFIR Tool, healthcare professionals identified a median number of six (range 1-11) facilitators and a median number of one (range 0-8) barrier. The factor most commonly identified as a facilitator was that the use of the PtDA is aligned with the healthcare professional's value, and the factor most commonly identified as a barrier was the lack of access to data to track the changes in outcomes related to the PtDA. Conclusion: The PtDA was found to be usable by patients based on PSSUQ scores. Healthcare professionals reported more facilitators than barriers to using the PtDA in the perioperative setting. However, few patients eligible for the study completed the PtDA in both centers, which may suggest ongoing challenges with implementing PtDAs in the perioperative setting. Additional research is required to assess clinical outcomes associated with its use in routine practice for patients, and address implementation barriers for providers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.028
metaresearch head score (Gemma)0.059
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.028
Threshold uncertainty score0.149

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0280.059
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.314
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2024
Admission routes2
Has abstractyes

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