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Record W4405098589 · doi:10.22215/etd/2024-16270

Advances in Monte Carlo modelling for characterization of specific energy and absorbed dose distributions from cell to patient length scales

2024· dissertation· en· W4405098589 on OpenAlexfundno aff
Elizabeth Mary Fletcher

Bibliographic record

Venuenot available
Typedissertation
Languageen
FieldMedicine
TopicRadiation Therapy and Dosimetry
Canadian institutionsnot available
FundersAlliance de recherche numérique du CanadaNatural Sciences and Engineering Research Council of CanadaCanada Research Chairs
KeywordsDosimetryRadiation therapyMonte Carlo methodComputer scienceMedical physicsRadiationPopulationScale (ratio)Absorbed doseDeposition (geology)Radiation treatment planningPhysicsStatistical physicsMedicineNuclear medicineMathematicsStatisticsOpticsRadiology

Abstract

fetched live from OpenAlex

Radiotherapy uses radiation for the diagnosis and treatment of disease, in particular cancer.To understand and improve radiotherapy techniques, an accurate understanding of energy deposition is needed.Computational radiation dosimetry uses physics to calculate expected energy deposition during radiotherapy treatments.This thesis uses computational techniques to advance radiation dosimetry in two domains: in the research environment, where computational models can be used to inform and guide the development of prospective radiotherapy treatments, and in the cancer clinic, where the adoption of more sophisticated computational techniques can lead to better patient outcomes.I would like to thank my supervisor, Dr. Rowan Thomson, for her guidance and support throughout my PhD studies.I have grown and improved as a scientist, writer, and person through your mentorship

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.018
Threshold uncertainty score0.036

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.011
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0020.001
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.250
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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