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Record W4405138906 · doi:10.1101/2024.12.06.627178

The brain selectively allocates energy to functional brain networks under cognitive control

2024· preprint· en· W4405138906 on OpenAlexaff
Jenny Rieck, Shamim Golafshan, Cheryl Grady, Bratislav Mišić, Benjamin T. Dunkley, Ali Khatibi

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2024
Typepreprint
Languageen
FieldNeuroscience
TopicEEG and Brain-Computer Interfaces
Canadian institutionsHospital for Sick ChildrenMcGill UniversityUniversity of TorontoBaycrest Hospital
Fundersnot available
KeywordsCognitionControl (management)Functional connectivityComputer scienceEnergy (signal processing)NeurosciencePsychologyCognitive psychologyArtificial intelligencePhysics

Abstract

fetched live from OpenAlex

Network energy has been conceptualized based on structural balance theory in the physics of complex networks. We utilized this framework to assess the energy of functional brain networks under cognitive control and to understand how energy is allocated across canonical functional networks during various cognitive control tasks. We extracted network energy from functional connectivity patterns of subjects who underwent fMRI scans during cognitive tasks involving working memory, inhibitory control, and cognitive flexibility, in addition to task-free scans. We found that the energy of the whole-brain network increases when exposed to cognitive control tasks compared to the task-free resting state, which serves as a reference point. The brain selectively allocates this elevated energy to canonical functional networks; sensory networks receive more energy to support flexibility for processing sensory stimuli, while cognitive networks relevant to the task, functioning efficiently, require less energy. Furthermore, employing network energy, as a global network measure, improves the performance of predictive modeling, particularly in classifying cognitive control tasks and predicting chronological age. Our results highlight the robustness of this framework and the utility of network energy in understanding brain and cognitive mechanisms, including its promising potential as a biomarker for mental conditions and neurological disorders.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.231
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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