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Record W4405156695 · doi:10.1002/cbdv.202402220

<i>Costus igneus</i>: A Versatile Herbal Remedy for Multiple Health Conditions

2024· review· en· W4405156695 on OpenAlexaff
Bhaskar Sahu

Bibliographic record

VenueChemistry & Biodiversity · 2024
Typereview
Languageen
FieldMedicine
TopicNatural Antidiabetic Agents Studies
Canadian institutionsColumbia College
Fundersnot available
KeywordsPhytochemicalTraditional medicineABTSDPPHChemistryHerbAntimicrobialAntioxidantTerpenoidMedicinal plantsPharmacologyMedicinal herbsMedicineBiochemistry

Abstract

fetched live from OpenAlex

Costus igneus, commonly known as the insulin plant, is a potent medicinal herb with a wide range of pharmacological activities. Traditionally used in diabetes management, recent studies have highlighted its antidiabetic, antioxidant, antimicrobial, hepatoprotective, and kidney stone-inhibitor properties. Phytochemical analyses reveal the presence of saponins, flavonoids, alkaloids, steroids, and terpenoids, which contribute to its therapeutic effects. In various in vitro and in vivo models, C. igneus demonstrated significant hypoglycemic activity. The plant exhibits strong antioxidant activity, as evidenced by FRAP, DPPH, and ABTS assays, with notable radical scavenging and reducing power. Other miscellaneous pharmacological activities include anti-inflammatory, anti-arthritic, cytotoxicity, and hypotensive effects. These findings support C. igneus as a safe and cost-effective herbal remedy for managing diabetes and other ailments, highlighting its potential for future therapeutic applications and the development of herbal formulations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.149
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.071
GPT teacher head0.356
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2024
Admission routes1
Has abstractyes

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