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Identification of Gram‐Positive Bacteria

2023· other· en· W4405232890 on OpenAlexaff
Kathryn Bernard

Bibliographic record

VenueClinMicroNow · 2023
Typeother
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBacterial Identification and Susceptibility Testing
Canadian institutionsPublic Health Agency of Canada
Fundersnot available
KeywordsIdentification (biology)GramBacteriaGram-negative bacteriaMicrobiologyComputational biologyBiologyGram-positive bacteriaGeneticsEscherichia coliBotanyGene

Abstract

fetched live from OpenAlex

Abstract Unlike in the case of Gram‐negative bacilli, it can be difficult to definitively identify Gram‐positive cocci and bacilli to the genus and species levels. Gram‐positive bacilli have been difficult to identify because pathogens have to be discerned from hundreds of validly named species that are found in the environment or are part of the normal microbiota of the human body, including the skin, mucosal membranes, oropharynx, and genitourinary and gastrointestinal tracts, and the taxonomy of such agents is both evolving and being augmented. For species‐level identification of viridans group streptococci, enterococci, and corynebacteria, commercial kits are often easier to perform than standard tube biochemical tests, but both approaches have limitations in accuracy. Because of the lack of unique colony morphologies for many Gram‐positive microorganisms, the Gram stain must be performed on isolates for identification. Gram‐variable microorganisms are considered Gram positive.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.596
Threshold uncertainty score0.715

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.279
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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