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Record W4405247714 · doi:10.1111/jvim.17253

A consort-guided randomized, blinded, controlled clinical trial on the effects of 6 weeks training on heart rate variability in thoroughbred horses

2024· article· en· W4405247714 on OpenAlexafffund
Emma Santosuosso, Renaud Léguillette, Sierra Shoemaker, Ryan Baumwart, Sierra Temple, Kaneesha Hemmerling, Tessa Kell, Warwick M. Bayly

Bibliographic record

VenueJournal of Veterinary Internal Medicine · 2024
Typearticle
Languageen
FieldVeterinary
TopicVeterinary Equine Medical Research
Canadian institutionsUniversity of Calgary
FundersUniversity of CalgaryWashington State University
KeywordsMedicinePhysical therapyHeart rate variabilityRandomized controlled trialHeart ratePhysical medicine and rehabilitationInternal medicineBlood pressure

Abstract

fetched live from OpenAlex

Abstract Background Fitness assessment of horses remains challenging. Heart rate variability (HRV) can be used to monitor human athlete's training, but its value is unknown in horses. Hypothesis The linear domain HRV variables are affected by fitness. Animals Twelve healthy untrained thoroughbreds were randomly split into a training group (6 weeks of incremental racetrack training) and a control group (no training). Methods Linear domain HRV variables were analyzed (high frequency [HF], low frequency [LF], their normalized units [Hfnu, Lfnu], root mean square of successive differences between beats [RMSSD], Poincaré plot features [SD1 and SD2]) while resting overnight before (baseline) and after 2, 4 and 6 weeks of training. V̇O2max and echocardiographic indexes were measured at baseline and after 6 weeks. Changes in HRV variables over time (ANOVA), and correlation with V̇O2max (Pearson's chi-squared test) were tested (P < .05 significance). Results V̇O2max, LF/HF ratio, and LFnu increased while HFnu decreased in the training group (before and after training mean [SD] values: V̇O2max 134 [12.8]-146 [16.5] mL/[kg min]; P < .001; LF/HF ratio 0.51 [0.2]-0.91 [0.3] [P = .02]; LFnu 37.5 [10.1]-46.8 [7.8] [P = .02]; HFnu 76.2 [7.9]-53.2 [7.7] [P < .001]). Training did not affect RMSSD, SD1, SD2, resting HR, or echocardiographic indexes. Strong correlations were found between V̇O2max and HRV variables (V̇O2max and LFnu [r = −0.59, P = .04]; ΔV̇O2max and the corresponding ΔLF [r = −0.88, P = .02]). Conclusions and Clinical Importance Six weeks of training affected some frequency domain HRV variables. Further studies are necessary to validate the use of HRV for monitoring horses' responses to training.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.046
metaresearch head score (Gemma)0.094
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Research integrity
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.197
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0460.094
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0040.001
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.004
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.285
GPT teacher head0.509
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2024
Admission routes2
Has abstractyes

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