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Record W4405364447 · doi:10.1101/2024.02.19.23300472

Automated visual acuity estimation by optokinetic nystagmus using a stepped sweep stimulus

2024· preprint· en· W4405364447 on OpenAlexaff
Jason Turuwhenua, Zaw LinTun, Mohammad Norouzifard, Misty Edmonds, Rebecca Findlay, J. L. Black, Benjamin Thompson

Bibliographic record

VenuemedRxiv · 2024
Typepreprint
Languageen
FieldNeuroscience
TopicVisual perception and processing mechanisms
Canadian institutionsUniversity of Waterloo
FundersHealth Research Council of New ZealandHong Kong Government
KeywordsOptokinetic reflexNystagmusStimulus (psychology)AudiologyComputer visionVisual acuityComputer scienceArtificial intelligencePsychologyEye movementMedicineOphthalmologyCognitive psychology

Abstract

fetched live from OpenAlex

ABSTRACT Purpose Measuring visual acuity (VA) can be challenging in adults with cognitive impairment and young children. We developed an automatic system for measuring VA using Optokinetic Nystagmus (OKN). Methods VA-OKN and VA by ETDRS (VA-ETDRS) were measured monocularly in healthy participants (n=23, age 30±12). VA was classified as reduced (n=22, >0.2 logMAR) or not (n=24, ≤0.2 logMAR) in each eye. VA-OKN stimulus was an array of drifting (5 deg/sec) vanishing disks presented in descending/ascending size order (0.0 to 1.0 logMAR in 0.1 logMAR steps). The stimulus was stepped every 2 seconds, and 10 sweeps were shown per eye. Eye tracking data determined when OKN activity ceased (descending sweep) or began (ascending sweep) to give an automated sweep VA. Sweep traces were randomized and assessed by a reviewer blinded to VA-ETDRS. A final per sweep VA and VA-OKN was thereby determined. Results A single randomly selected eye was used for analysis. VA deficit group: There was no significant difference between overall mean VA-OKN and VA-ETDRS (p>0.05, paired t-test) and the r 2 statistic was 0.84. The 95% limits of agreement were 0.19 logMAR. No VA deficit group: There was a 0.24 logMAR bias between VA-OKN and VA-ETDRS and no correlation was found (r 2 = 0.06). However, the overall sensitivity/specificity for classification was 100%. Conclusions A robust correlation between VA-ETDRS and VA-OKN was found. The method correctly detected a VA deficit. Translational relevance OKN is a promising method for measuring VA in cognitively impaired adults and pre-verbal children.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.064
GPT teacher head0.382
Teacher spread0.318 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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