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Record W4405625235 · doi:10.1016/s2589-7500(24)00241-3

The importance of microbiology reference laboratories and adequate funding for infectious disease surveillance

2024· review· en· W4405625235 on OpenAlex
David R. Shaw, Raquel Abad Torreblanca, Zahin Amin‐Chowdhury, Désirée E. Bennett, Karen Broughton, Carlo Casanova, Eun Hwa Choi, Heike Claus, Mary Corcoran, Simon Cottrell, Robert Cunney, Lize Cuypers, Tine Dalby, Heather Davies, Linda de Gouveia, Ala‐Eddine Deghmane, Stefanie Desmet, Mirian Domenech, Richard J. Drew, Mignon du Plessis, Carolina Duarte, Kurt Fuursted, Alyssa Golden, Samanta Cristine Grassi Almeida, Desirée Henares, Birgitta Henriques‐Normark, Markus Hilty, Steen Hoffmann, H. Humphreys, Susanne Jacobsson, Christopher R. Johnson, Keith A. Jolley, Aníbal Kawabata, Jana Kozáková, Karl G. Kristinsson, Pavla Křížová, Alicja Kuch, Shamez Ladhani, Thiên‐Trí Lâm, Laura Lindholm, David Litt, Martin Maiden, Irene Martín, Delphine Martiny, Wesley Mattheus, Noel McCarthy, Mary Meehan, Susan Meiring, Paula Mölling, Eva Morfeldt, Julie Morgan, Robert Mulhall, Carmen Muñoz‐Almagro, David R. Murdoch, Martin Musílek, Ludmila Nováková, Shahin Oftadeh, Amaresh Pérez-Argüello, Marı́a Pérez-Vázquez, Monique Perrin, Benoît Prévost, Maria Roberts, Assaf Rokney, M. Ron, Olga Sanabria, Kevin J Scott, Julio Sempere, Lotta Siira, Ana Paula Silva de Lemos, Vitali Sintchenko, Anna Skoczyńska, Hans‐Christian Slotved, Andrew Smith, Muhamed‐Kheir Taha, Maija Toropainen, Georgina Tzanakaki, Anni Vainio, Mark P. G. van der Linden, Nina M. van Sorge, Emmanuelle Varon, Julio A. Vázquez, Sandra Vohrnova, Anne von Gottberg, José Yuste, Angela B. Brueggemann

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueThe Lancet Digital Health · 2024
Typereview
Languageen
FieldMedicine
TopicZoonotic diseases and public health
Canadian institutionsPublic Health Agency of Canada
FundersMinisterstwo ZdrowiaNarodowy Instytut LekówFolkhälsomyndighetenRWTH Aachen UniversityInstitute of Environmental Science and ResearchABBRobert Koch InstitutUniversity of OtagoTrinity College DublinBundesministerium für GesundheitMinisterstwo Edukacji i NaukiPublic Health AgencyEuropean Centre for Disease Prevention and ControlUniversity of OxfordPfizerPublic Health WalesWellcome TrustUniversity of Bern
KeywordsInfectious disease (medical specialty)Clinical microbiologyDisease surveillanceMedicineEnvironmental healthMicrobiologyDiseaseBiologyInternal medicine

Abstract

fetched live from OpenAlex

Microbiology reference laboratories perform a crucial role within public health systems. This role was especially evident during the COVID-19 pandemic. In this Viewpoint, we emphasise the importance of microbiology reference laboratories and highlight the types of digital data and expertise they provide, which benefit national and international public health. We also highlight the value of surveillance initiatives among collaborative international partners, who work together to share, analyse, and interpret data, and then disseminate their findings in a timely manner. Microbiology reference laboratories have substantial impact at regional, national, and international levels, and sustained support for these laboratories is essential for public health in both pandemic and non-pandemic times.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Not applicablelow
gptno category
Domain: not available · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Other designmedium
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.980
Threshold uncertainty score0.578

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.097
GPT teacher head0.408
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it