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To kill or to piggyback: Switching of viral lysis-lysogeny strategies depending on host dynamics

2024· article· en· W4405741514 on OpenAlexaff
Chen Hu, Xiaowei Chen, Wei Wei, Douglas W.R. Wallace, Jihua Liu, Yao Zhang, Lianbao Zhang, Dapeng Xu, John Batt, Xilin Xiao, Qiang Shi, Qiang Zheng, Ruijie Ma, Tingwei Luo, Nianzhi Jiao, Rui Zhang

Bibliographic record

VenueThe Science of The Total Environment · 2024
Typearticle
Languageen
FieldEnvironmental Science
TopicBacteriophages and microbial interactions
Canadian institutionsDalhousie University
FundersNatural Science Foundation of Fujian ProvinceNational Natural Science Foundation of China
KeywordsLysogenic cycleHost (biology)LysisBiologyVirologyBacteriophageGeneticsImmunologyEscherichia coli

Abstract

fetched live from OpenAlex

Viruses wield significant influence over microbial communities and ecosystem function in marine environments. However, the selection of viral life strategies and their impacts on microbial communities remains enigmatic. In this study, we utilized a large-scale macrocosm, established using water samples from a marine coastal region, to enable community-level investigation. Through a prolonged incubation experiment, we aimed to clarify the ramifications of lytic and lysogenic viral activities on microbial community dynamics. We observed a continuous succession in bacterial abundance, growth rate, and community diversity, tightly linked with time series switching between viral lysis and lysogeny. Elevated lytic viral production notably fostered greater bacterial diversity, whereas increased lysogenic viral production corresponded to bacterial communities characterized by heightened abundance and growth rate but reduced diversity. Moreover, discernible shifts in bacterial community compositions, associated with different abundant bacterial taxa, were synchronized with pronounced transitions between viral lysis and lysogeny. Notably, the switch from lysogeny to lysis facilitated the proliferation of initially rare bacterial populations. Our findings suggest that the Kill-the-Winner and Piggyback-the-Winner hypotheses, both elucidating dynamic patterns in virus-host interactions, can synergistically demonstrate the pivotal role of viruses in regulating microbial communities via the lysis-lysogeny switch in marine environments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.245
Teacher spread0.236 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2024
Admission routes1
Has abstractyes

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