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Record W4405774778 · doi:10.54029/2024upf

Pattern of cognitive deficit in vascular dementia

2024· article· en· W4405774778 on OpenAlexaboutno aff
Junita Maja Pertiwi, Ansye Grace Nancy Momole, Finny Warouw, Gilbert Tangkudung, Aristo Pangestu, Glensy Iroth

Bibliographic record

VenueNeurology Asia · 2024
Typearticle
Languageen
FieldNeuroscience
TopicNeurological Disorders and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsVascular dementiaDementiaCognitive deficitCognitionPsychologyCognitive psychologyMedicineNeuroscienceCognitive impairmentInternal medicineDisease

Abstract

fetched live from OpenAlex

Background: Vascular dementia (VaD) is the second most common cause of dementia after Alzheimer’s disease. Vascular dementia has heteregeneous manifestation due to varying infarct location and subtypes. Despite quite frequent in Indonesia due to high incidence of stroke, the study about pattern of cognitive deficit in vascular dementia are still limited. Methods: This study is an observational cross-sectional consecutive sampling study conducted at the Memory Clinic of Provincial General Hospital Prof. Dr. R.D.Kandou, Manado, North Sulawesi, Indonesia during the period 1 January 2023 to 31 March 2024. Vascular dementia was diagnosed based on NINDS-AIREN criteria, and further classified based on Vascular Impairment of Cognition Classification Consensus Study (VICCCS). Cognitive examinations were done by using the Indonesian version of the Montreal Cognitive Assessment instrument (MoCA- INA) and other cognitive examinations. Results: There were 100 subjects who met the inclusion and exclusion criteria. The mean MoCA-INA in the study subjects was 12.2 (SD ± 6.0), with the lowest value found in mixed type dementia followed by multiple infarction/cortical and subcortical vascular dementia. Memory was the domain that most frequently impaired in vascular dementia. Impairments in the language domain were more common in the multiple infarct/cortical subtype, while executive function deficits were more frequently found in the subcortical subtype of vascular dementia (p<0.001). Attention, memory and visuospatial disorders did not show any significant differences in the three subtypes of vascular dementia. Conclusion: Language disorders are more common in multiple infarction or cortical subtypes, while executive function is more dominantly impaired in the cortical subtype.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.168
Threshold uncertainty score0.415

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.266
Teacher spread0.245 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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