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Record W4405840119 · doi:10.1002/9781119912576.ch4

The genetics of the dental occlusion and malocclusion

2024· other· en· W4405840119 on OpenAlexaff
Robyn Silberstein, Mary MacDougall

Bibliographic record

Venuenot available
Typeother
Languageen
FieldBiochemistry, Genetics and Molecular Biology
Topicdental development and anomalies
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMalocclusionOrthodonticsOcclusionMedicineGeneticsBiologyDentistryInternal medicine

Abstract

fetched live from OpenAlex

Birth defects are due to a combination of environmental and genetic factors. This chapter provides examples of some common craniofacial, orofacial, and dental anomalies and special treatment considerations required by orthodontists. A patient may present with a confirmed genetic diagnosis, but observant clinical examination is often the initial clue to an important genetic contribution. Consequences of the presence of any single etiologic factor differ from one embryologic environment to another. The complexity of determining contributions of multiple genetic, environmental, and growth interactions to the complex inheritance traits of a Class II or III malocclusion is a challenge. The number of single gene mutations associated with craniofacial anomalies is extensive. Alterations of tooth number, size, and shape are common craniofacial anomalies, while structure and eruption problems are less frequent. Anomalies of tooth structure involve three specialized calcified hard tissues: enamel, dentin, and cementum.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.048
Threshold uncertainty score0.221

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.213
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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