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Record W4405851924 · doi:10.5376/gab.2024.15.0020

Genome Editing and Rice Improvement: The Role of CRISPR/Cas9 in Developing Superior Yield Traits

2024· article· en· W4405851924 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueGenomics and Applied Biology · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCRISPR and Genetic Engineering
Canadian institutionsnot available
Fundersnot available
KeywordsCRISPRGenome editingYield (engineering)BiologyGeneticsBiotechnologyComputational biologyGene

Abstract

fetched live from OpenAlex

The study demonstrated that the CRISPR/Cas9 system is highly efficient in rice, with nearly half of the target genes edited in the first generation of transformed plants (T0). The mutations were found to be heritable, following classic Mendelian inheritance patterns, with no detectable large-scale off-target effects. Additionally, the CRISPR/Cas9 system enabled high-efficiency multiplex genome editing, allowing for the simultaneous targeting of multiple genes, which is crucial for improving complex traits such as yield. The use of CRISPR/Cas9 has also been shown to enhance grain quality and other agronomic traits, making it a versatile tool for rice improvement. The findings underscore the potential of the CRISPR/Cas9 system as a powerful and precise tool for rice genome engineering. By enabling targeted and heritable gene modifications with minimal off-target effects, CRISPR/Cas9 can significantly contribute to the development of rice varieties with superior yield traits. This technology holds promise for addressing global food security challenges by improving rice productivity and quality.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.060
Threshold uncertainty score0.345

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.249
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it