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Record W4405851934 · doi:10.5376/gab.2024.15.0023

Genome-Wide Association Studies in Fabaceae: Progress and Prospects

2024· article· en· W4405851934 on OpenAlexvenueno aff
Qishan Chen

Bibliographic record

VenueGenomics and Applied Biology · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic Mapping and Diversity in Plants and Animals
Canadian institutionsnot available
Fundersnot available
KeywordsFabaceaeGenome-wide association studyComputational biologyBiologyAssociation (psychology)GenomeEvolutionary biologyGeneticsGeneEcologyPsychologySingle-nucleotide polymorphismGenotype

Abstract

fetched live from OpenAlex

Recent advancements in GWAS have significantly enhanced our understanding of the genetic architecture of complex traits in Fabaceae. Key discoveries include the identification of numerous genomic variants linked to agronomic traits, such as yield, stress tolerance, and biochemical properties. The development of novel methodologies, such as mixed model frameworks and haplotype-based fine-mapping, has improved the accuracy and resolution of GWAS, reducing false positives and increasing the power to detect rare variants. Additionally, the integration of next-generation sequencing technologies has facilitated the rapid identification of candidate genes and their functional validation. The findings from GWAS in Fabaceae have profound implications for plant breeding and genetic engineering. By uncovering the genetic basis of complex traits, these studies provide valuable insights that can be leveraged to enhance crop performance and resilience. Future research should focus on optimizing GWAS models, exploring epistatic interactions, and utilizing genomic data to advance our understanding of biological processes and improve crop breeding strategies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.025
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.025
Threshold uncertainty score0.135

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0250.011
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.004
Science and technology studies0.0010.002
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.253
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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