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Record W4405919802 · doi:10.61373/gp024k.0100

Michael Meaney: What is the biology that underlies the gene x environment interdependence that shapes brain health?

2024· article· en· W4405919802 on OpenAlexaffabout
Michael J. Meaney

Bibliographic record

VenueGenomic psychiatry : · 2024
Typearticle
Languageen
FieldEnvironmental Science
TopicHealth, Environment, Cognitive Aging
Canadian institutionsMcGill UniversityDouglas Mental Health University Institute
Fundersnot available
KeywordsBiologyGeneComputational biologyGeneticsEvolutionary biologyCognitive sciencePsychology

Abstract

fetched live from OpenAlex

As a distinguished James McGill Professor and now Professor Emeritus at McGill University, Michael Meaney's scientific journey is a testament to the power of curiosity in science. His fascination with how our environment shapes our genes, brain function, and mental health has led to discoveries that have changed how we think about human development. After leading groundbreaking research at McGill, he took his expertise to Singapore, where, as Director of the Translational Neuroscience program at ASTAR, he helped shape the innovative GUSTO birth cohort study. His profound impact on neuroscience is reflected not just in his impressive collection of honors – from the Order of Canada to his recent election to the American Academy of Arts and Sciences – but in how his work has touched lives. With over 650 publications to his name, Meaney has helped bridge the gap between molecular biology and public health. We are fortunate to have him share his insights with our readers in this Genomic Press Interview.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.767
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.272
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes2
Has abstractyes

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