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Record W4405919802 · doi:10.61373/gp024k.0100

Michael Meaney: What is the biology that underlies the gene x environment interdependence that shapes brain health?

2024· article· en· W4405919802 on OpenAlexaffabout
Michael J. Meaney

Bibliographic record

VenueGenomic psychiatry : · 2024
Typearticle
Languageen
FieldEnvironmental Science
TopicHealth, Environment, Cognitive Aging
Canadian institutionsMcGill UniversityDouglas Mental Health University Institute
Fundersnot available
KeywordsBiologyGeneComputational biologyGeneticsEvolutionary biologyCognitive sciencePsychology

Abstract

fetched live from OpenAlex

As a distinguished James McGill Professor and now Professor Emeritus at McGill University, Michael Meaney's scientific journey is a testament to the power of curiosity in science. His fascination with how our environment shapes our genes, brain function, and mental health has led to discoveries that have changed how we think about human development. After leading groundbreaking research at McGill, he took his expertise to Singapore, where, as Director of the Translational Neuroscience program at ASTAR, he helped shape the innovative GUSTO birth cohort study. His profound impact on neuroscience is reflected not just in his impressive collection of honors – from the Order of Canada to his recent election to the American Academy of Arts and Sciences – but in how his work has touched lives. With over 650 publications to his name, Meaney has helped bridge the gap between molecular biology and public health. We are fortunate to have him share his insights with our readers in this Genomic Press Interview.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.012
Threshold uncertainty score0.025

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.013
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0030.005
Scholarly communication0.0040.007
Open science0.0010.002
Research integrity0.0050.011
Insufficient payload (model declined to judge)0.0060.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.272
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes2
Has abstractyes

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