Map-dot-fingerprint (epithelial basement membrane) corneal dystrophy: A clinicopathological study
Bibliographic record
Abstract
Abstract Background: Map-dot-fingerprint (MDF) is a corneal epithelial dystrophy affecting the basement membrane that presents bilaterally or in an asymmetric manner. Clinically, it appears as opacities or fingerprint lines and histopathologically, microcystic structures, dot-like patterns, or basement membrane thickening are commonly described features. Materials and Methods: We conducted a retrospective study on 10 cases of MDF obtained from 9 patients between 2017 to 2018 from the MUHC-McGill Ocular Pathology & Translational Research Laboratory. Results: Following histopathological evaluation with hematoxylin and eosin, periodic acid–Schiff (PAS), and in one case Alcian Blue, a final diagnosis of MDF was reached in all cases. Conclusion: This case series aims to document MDFs histopathological characteristics. To the best of our knowledge, this is the largest case series with histopathological diagnosis published, filling an important gap in the literature.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".