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Record W4406047229 · doi:10.15562/bmj.v13i3.5345

Correlation of triple diagnostic (clinical, thyroid ultrasound, and FNAB) with histopathology in thyroid cancer patient

2024· article· en· W4406047229 on OpenAlexaboutno aff
Sasongko Hadi Priyono, Hari Subagiyo, Kenanga Marwan Sikumbang, Husna Dharma Putera, Winardi Budiwinata, Audi Ardansyah, Huldani Huldani

Bibliographic record

VenueBali Medical Journal · 2024
Typearticle
Languageen
FieldMedicine
TopicRadiomics and Machine Learning in Medical Imaging
Canadian institutionsnot available
Fundersnot available
KeywordsHistopathologyMedicineThyroid cancerThyroidRadiologyUltrasoundPathologyInternal medicine

Abstract

fetched live from OpenAlex

Background: A thyroid nodule is a thyroid gland lesion that can be benign or malignant. The diagnosis was made based on clinical, radiological, and pathological findings, including McGill Thyroid Nodule Score (MTNS) for risk estimation, ultrasound using TIRADS criteria, and also fine needle aspiration biopsy (FNAB), which detected malignancy. However, the accuracy varied. The combination of these 3 diagnostic methods provides a better accuracy. This study aims to determine the correlation of triple diagnostics with histopathology in thyroid cancer patients. Method: This is a retrospective observational analytical study of thyroid nodule patients in Ulin Hospital from 2018 to 2022. Inclusion criteria in this study include patients with complete triple diagnostic data (clinical symptom, USG thyroid, and FNAB). Patients with incomplete data were excluded. Variables collected included demography, histopathology, symptom, ultrasonography (USG), and FNAB results. Data was analyzed with SPSS software using Spearman correlation and logistic regression tests. Results: A positive and statistically significant correlation between thyroid cancer with MTNS (r = 0.352, p = 0.002) and Bathesda (r = 0.240, p = 0.034) was discovered. A positive correlation was also found between TIRADS and thyroid cancer (r = 0.158) but not statistically significant (p>0,05). The combination of MTNS, TIRADS, and FNAB produced a strong positive and significant correlation (r = 0.510, p = 0.008) with thyroid cancer. Conclusion: MTNS and Bathesda categorization significantly correlated with thyroid cancer histopathology, while the TIRADS category presented a meaningless relationship. Triple diagnostics revealed a stronger and more significant correlation with histopathology in thyroid cancer patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.261
Threshold uncertainty score0.750

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.319
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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