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Record W4406090990 · doi:10.58931/cibdt.2024.2334

Recent Advances in Complementary and Alternative Therapies for Inflammatory Bowel Disease

2024· article· en· W4406090990 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueCanadian IBD Today · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsMount Sinai Hospital
Fundersnot available
KeywordsInflammatory bowel diseaseMedicineInflammatory Bowel DiseasesIntensive care medicineDiseaseInternal medicine

Abstract

fetched live from OpenAlex

Inflammatory bowel disease (IBD) is a chronic relapsing-remitting inflammatory condition of the gastrointestinal (GI) tract, primarily comprised of 2 major types: Crohn's disease (CD) and ulcerative colitis (UC). The pathogenesis of IBD is not fully elucidated but is thought to be multifactorial involving genetic, environmental, and immunological contributors. The incidence of IBD has been rising worldwide, particularly in developed nations. Canada, in particular, has one of the highest prevalence rates of IBD globally, with recent data indicating that over 320,000 Canadians are living with IBD, making it a significant public health concern. The chronic nature of IBD, along with the severity of its symptoms, and the adverse effects occasionally attributed to management (e.g. immunosuppression, corticosteroids, surgical complications) can significantly reduce the quality of life for those affected. As such, many patients with IBD use complementary and alternative medicine (CAM) due to safety concerns of conventional therapy and a sense of greater control over their disease. CAM refers to a broad range of healthcare practices, such as herbal medicine, acupuncture, homeopathy, fecal microbiota transplants, and probiotics, which are not typically considered part of conventional western medicine. The use of CAM among patients with IBD is high, with current or past use of CAM ranging from 21-60% of IBD patients. Given the propensity of patients with IBD to seek CAM and the unfamiliarity that many medical practitioners have with the evidence of benefit/harm from these practices, this review seeks to summarize recent advances in clinical research on CAM use for IBD.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.824
Threshold uncertainty score0.917

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.252
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it