Outcomes of Antibiotic Therapy During Perinatal Period for the Early Age Child’s Intestinal Microbiota
Why this work is in the frame
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Bibliographic record
Abstract
This literature review provides data on antibiotic therapy (AT) consequences that child may be exposed during the perinatal period considering the development of the most crucial body system — intestinal microbiota. The main characteristics of the intestinal microbiota disturbance in infants due to various AT exposure time and volume are presented. Moreover, antibiotics' effects on the intestinal microbiota development in full-term and premature babies are covered. Modern data on the development of pathobionts and symbionts resistome within intestinal microbiota in «mother-child» complex and variants of vertical (from mother to child) and horizontal (between microorganisms) transmission of antibiotic resistance genes are presented. The major strategies for minimizing the negative consequences of perinatal AT are described
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it