MétaCan
Menu
Back to cohort
Record W4406109720 · doi:10.1039/d4tb02181a

Formulation and evaluation of PVA-based composite hydrogels: physicochemical, leachables, and <i>in vitro</i> immunogenicity studies

2025· article· en· W4406109720 on OpenAlexfundno aff
Achmad Himawan, Anna Korelidou, Ana M. Pérez‐Moreno, Juan L. Paris, Juan Domínguez‐Robles, Lalitkumar K. Vora, Andi Dian Permana, Eneko Larrañeta, Robert P. Graham, Christopher J. Scott, Ryan F. Donnelly

Bibliographic record

VenueJournal of Materials Chemistry B · 2025
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicAdvanced Drug Delivery Systems
Canadian institutionsnot available
FundersHORIZON EUROPE Marie Sklodowska-Curie ActionsEuropean Social FundQueen's University BelfastAgencia Estatal de InvestigaciónMinisterio de Ciencia e InnovaciónQueen's UniversityEuropean Commission
KeywordsImmunogenicitySelf-healing hydrogelsIn vitroComposite numberMaterials scienceChemistryBiomedical engineeringPharmacologyComposite materialMedicineImmunologyBiochemistryPolymer chemistryImmune system

Abstract

fetched live from OpenAlex

assays using DC2.4 mouse dendritic cells showed that hydrogel extracts inhibited cell proliferation without causing cytotoxicity or triggering significant immune responses. These findings highlight the hydrogels' biocompatibility and stability, supporting their potential for biomedical applications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.468

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.086
GPT teacher head0.429
Teacher spread0.342 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations15
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Materials Chemistry BSame topicAdvanced Drug Delivery SystemsFrench-language works237,207