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Record W4406116363 · doi:10.1093/cercor/bhae492

Identifying causal neural oscillations underlying working memory

2025· article· en· W4406116363 on OpenAlexafffund
Mina Mirjalili, Reza Zomorrodi, Zafiris J. Daskalakis, Daniel M. Blumberger, Sean Hill, Tarek K. Rajji

Bibliographic record

VenueCerebral Cortex · 2025
Typearticle
Languageen
FieldComputer Science
TopicCognitive Science and Mapping
Canadian institutionsUniversity of TorontoCentre for Addiction and Mental Health
FundersNational Institute of Mental HealthOntario Ministry of Research and InnovationNational Institutes of HealthOntario Ministry of Health and Long-Term CareMagVentureCanadian Institutes of Health ResearchWeston Brain InstituteCentre for Addiction and Mental Health FoundationBrainsWayBrightFocus FoundationFondation Brain CanadaIndiviorUniversity of TorontoBiogen
KeywordsWorking memoryNeuroscienceCognitive psychologyPsychologyComputer scienceCognitive scienceCognition

Abstract

fetched live from OpenAlex

Electroencephalography is instrumental in understanding neurophysiological mechanisms underlying working memory. While numerous studies have associated electroencephalography features to working memory, understanding causal relationships leads to better characterization of the neurophysiological mechanisms that are directly linked to working memory. Personalized causal modeling is a tool to discover these direct links between brain features and working memory performance. Therefore, we applied this approach to electroencephalography data from 66 adult healthy participants collected while performing a 3-back working memory task. Using graphical causal modeling, we discovered causal neural oscillations of working memory performance and compared the causal features between two groups: high and low performers. Total number of causal features in high performers was higher than low performers. Among the causal features, right temporal gamma oscillation was ~5 times (z-score = 3.87, P = 0.0001) more frequently a causal feature among high performers than low performers. However, the power of causal temporal gamma oscillation was not different between the two groups. Our findings suggest that one potential approach to improve working memory performance is to induce more causal gamma oscillations. This can be achieved by generating more local gamma entrainment over the right temporal cortex, rather than simply increasing gamma power.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.837
Threshold uncertainty score0.554

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.072
GPT teacher head0.320
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

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