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Record W4406153398 · doi:10.14740/jnr853

Spontaneous Subdural Hematoma Secondary to Influenza Vaccine-Induced Immune Thrombocytopenia

2025· article· en· W4406153398 on OpenAlexvenueno aff
Hesham Kelani, Izabella Beniaminova, Emina Dzafic, Priya Srivastava, Noor El-Deen Farghaly, Lauren Hatcher, Mohammad Jadidi, Diana Greene‐Chandos, Lisa R. Merlin

Bibliographic record

VenueJournal of Neurology Research · 2025
Typearticle
Languageen
FieldMedicine
TopicHeparin-Induced Thrombocytopenia and Thrombosis
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineImmune thrombocytopeniaInfluenza vaccineImmune systemHematomaImmunologyVirologyAntibodySurgeryVaccination

Abstract

fetched live from OpenAlex

Influenza vaccine-induced immune thrombocytopenia (ITP), though rare, can present with a wide spectrum of clinical manifestations, ranging from mild asymptomatic thrombocytopenia to life-threatening complications, such as gastrointestinal (GI) bleeding, diffuse alveolar hemorrhage (DAH), or intracranial hemorrhage (ICH), particularly when platelet count drops below a critical level of less than 5,000/µL. We report a rare case of spontaneous subdural hematoma (SDH) due to severe ITP following the influenza vaccine that showed a dramatic response to high-dose methylprednisolone and intravenous immunoglobulin (IVIG), with platelet count returning to normal and complete resolution of symptoms by the third day of therapy initiation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.822
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.004
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.080
GPT teacher head0.423
Teacher spread0.343 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Neurology ResearchSame topicHeparin-Induced Thrombocytopenia and ThrombosisFrench-language works237,207