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Sex differences in resting-state fMRI functional connectivity related to humor styles

2025· article· en· W4406160109 on OpenAlexaff
Chia-Yueh Chang, Yu‐Chen Chan, I-Fei Chen, Hsueh‐Chih Chen

Bibliographic record

VenueBiological Psychology · 2025
Typearticle
Languageen
FieldPsychology
TopicHumor Studies and Applications
Canadian institutionsRoyal Ottawa Mental Health Centre
FundersInstitute for Research Excellence in Learning Sciences, National Taiwan Normal University
KeywordsResting state fMRIFunctional connectivityPsychologyNeuroscienceDefault mode networkCognitive psychology

Abstract

fetched live from OpenAlex

Research on how functional connectivity (FC) during resting-state relates to humor styles and sex is limited. This study aimed to address this knowledge gap by analyzing resting-state fMRI data from 56 healthy participants and measuring FC. In addition, participants completed the Humor Styles Questionnaire. We found distinct FC patterns linked to humor styles that differed by sex. Men demonstrated stronger FC between the anterior cingulate cortex (ACC) and the right anterior insula (rAI), right inferior frontal gyrus (rIFG) and right frontal pole (rFP), and between the right rostral prefrontal cortex (rRPFC) and rIFG. These patterns were associated with aggressive and self-enhancing humor. Conversely, women exhibited stronger FC between rRPFC and the posterior cingulate gyrus (PCC), left rostral prefrontal cortex (lRPFC) and right thalamus, correlating with self-defeating and less aggressive humor. These findings suggest a neurobiological basis for sex differences in humor, indicating that men's FC between the salience network (SN), particularly in cognitive monitoring regions, may be linked to aggressive humor. Their FC between the executive control network (ECN) and between the SN and ECN are related to self-enhancing humor and reflect an emphasis on executive function. Conversely, women's FC between the SN and default mode network is correlated with self-defeating humor, suggesting a stronger focus on self-reflection and social relationships.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.022

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0070.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.400
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2025
Admission routes1
Has abstractno

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