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Record W4406167752 · doi:10.1016/j.ostima.2024.100260

Wireless vs. traditional ultrasound assessed knee cartilage outcomes utilizing automated gain and normalization techniques

2025· article· en· W4406167752 on OpenAlexaff
Arjun Parmar, Corey D. Grozier, Robert Dima, Jessica Tolzman, Ilker Hacihaliloglu, Kenneth L. Cameron, Ryan Fajardo, Matthew S. Harkey

Bibliographic record

VenueOsteoarthritis Imaging · 2025
Typearticle
Languageen
FieldMedicine
TopicOsteoarthritis Treatment and Mechanisms
Canadian institutionsUniversity of British ColumbiaWestern University
FundersNational Institute of Arthritis and Musculoskeletal and Skin Diseases
KeywordsNormalization (sociology)UltrasoundComputer scienceWirelessMedicineBiomedical engineeringRadiologyTelecommunications

Abstract

fetched live from OpenAlex

Advancements in wireless ultrasound technology allow for point of care cartilage imaging, yet validation against traditional ultrasound units remains to be established for knee cartilage outcomes. Therefore, the purpose of our study was to establish the replicability, reliability and agreement, of articular cartilage thickness and echo-intensity measures between traditional and wireless ultrasound units utilizing automatic-gain and normalization techniques. We used traditional and wireless ultrasound to assess the femoral cartilage via transverse suprapatellar scans with the knee in maximum flexion in 71 female NCAA Division I athletes (age: 20.0±1.3 years, height: 171.7±8.7 cm, mass: 69.4±11.0 kg). Wireless ultrasound images (auto-gain and standard gain) were compared to traditional ultrasound images (standard gain) before and after normalization. Ultrasound image pixel values were algebraically scaled to normalize differences between units in image acquisition. Mean thickness and echo-intensity of the global and sub-regions of interest were measured across imaging parameters. Intraclass correlation coefficients (ICC 2, k ) for reliability, standard error of the measurement, minimum detectable difference, and Bland-Altman plots for agreement were calculated between ultrasound units across imaging parameters. Cartilage thickness demonstrated good to excellent reliability (ICC 2,k =0.83–0.95) and minimal bias (-0.06–0.03 mm), in all regions regardless of gain and normalization. However, mean echo-intensity demonstrated poor to moderate reliability (ICC 2,k =0.23–0.68) and moderate bias (-9.8–6.5 au) in all regions, regardless of gain and normalization. While there was a high level of replicability between units when assessing cartilage thickness, further research in ultrasound beam forming may lead to improvements in replicability of cartilage echo-intensity between ultrasound units.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.384
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.265
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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