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Record W4406220486 · doi:10.1002/ajim.23700

Risk of Raynaud's Phenomenon Among Workers in the Occupational Disease Surveillance System

2025· article· en· W4406220486 on OpenAlexaffabout
Ryann E. Yeo, Fanni R. Eros, Paul A Demers, Jeavana Sritharan

Bibliographic record

VenueAmerican Journal of Industrial Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicSystemic Sclerosis and Related Diseases
Canadian institutionsPublic Health OntarioUniversity of TorontoOccupational Cancer Research Centre
Fundersnot available
KeywordsMedicineHazard ratioConfidence intervalCohortOccupational medicineProportional hazards modelCohort studyEpidemiologyDemographySurgeryInternal medicine

Abstract

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INTRODUCTION: Raynaud's phenomenon (RP) is linked to occupational exposures such as vibration, cold temperature, and chemicals. However, large cohort studies examining RP by occupation and sex are scarce. To address this gap, this study aimed to assess risk of RP by both occupation and sex in a large cohort of workers in Ontario, Canada. METHODS: Workers with accepted lost-time compensation claims were linked to physician billing records to identify diagnoses of RP between 2002 and 2020. A 3-year washout (disease-free) period was applied, and follow-up was limited to 5 years. Cox proportional hazard models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for diagnoses of RP, adjusted for age at start of follow-up, birth year, and stratified by sex. RESULTS: A total of 7,131 RP cases were identified among 810,739 workers. Among men, higher risks were observed for truck drivers (HR = 1.23, 95% CI = 1.08-1.41), driver-salesmen (HR = 2.54, 95% CI = 1.21-5.34), those in mining and quarrying-related cutting, handling, and loading (HR = 2.57, 95% CI = 1.29-5.15), and construction trades laboring and elemental work (HR = 1.70, 95% CI = 1.24-2.34). Among women, higher risks were observed for those working in waitressing and related (HR = 1.70, 95% CI = 1.22-2.38), food and beverage preparation (HR = 1.34, 95% CI = 1.02-1.76), and electrical equipment fabricating and assembling (HR 1.96, 95% CI = 1.08-3.55). CONCLUSION: Study findings show elevated risks of RP among various occupations, with notable differences between men and women. These differences may be attributable to variations in potential exposures and susceptibility to RP. Findings underscore the need for large cohort studies to examine RP across various occupational groups and both sexes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.704
Threshold uncertainty score0.595

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.282
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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