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Record W4406378677 · doi:10.1111/pce.15374

Early Initiation of Bundle Sheath Cells During Leaf Development as Visualised by SCARECROW Expression in Dicotyledonous C<sub>4</sub> Plants

2025· article· en· W4406378677 on OpenAlexafffund
Yuri Munekage, Yukimi Y. Taniguchi, Ken Okudono, Tammy L. Sage

Bibliographic record

VenuePlant Cell & Environment · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicPlant Molecular Biology Research
Canadian institutionsUniversity of Toronto
FundersJapan Society for the Promotion of ScienceNatural Sciences and Engineering Research Council of Canada
KeywordsBiologyVascular bundleAuxinBotanyCell biologyMutantWild typeReporter geneArabidopsis thalianaArabidopsisGene expressionMolecular biologyGeneBiochemistry

Abstract

fetched live from OpenAlex

ABSTRACT The C 4 type of dicotyledonous plants exhibit a higher density of reticulate veins than the C 3 type, with a nearly 1:1 ratio of mesophyll cells (MCs) to bundle sheath cells (BSCs). To understand how this C 4 ‐type cell pattern is formed, we identified two SCARECROW (SCR) genes in C 4 Flaveria bidentis, FbSCR1 and FbSCR2 , that fully or partially complement the endodermal cell layer‐defective phenotype of Arabidopsis scr mutant. We then created FbSCRs promoter β‐glucuronidase reporter (GUS) lines of F. bidentis , which showed GUS expression in BSCs and their progenitor cells. The GUS expression pattern in F. bidentis transformants and comparison with the closely related C 3 ‐type Flaveria pringlei revealed that higher‐order veins were initiated in the early leaf developmental stage. Treatment with an auxin polarity transport inhibitor decreased the MC area and led to vein formation without free ends, resulting in the formation of BSCs in positions adjacent to other BSCs. However, BSC differentiation was not affected, as evidenced by BSC specific FbSCR1 expression and RuBisCO accumulation. These results indicate that polar auxin transport is important for MC proliferation and/or differentiation, which leads to the formation of a C 4 ‐type cell pattern in which MCs and BSCs are equally adjacent.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.112
Threshold uncertainty score0.402

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.196
Teacher spread0.188 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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