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Record W4406525618 · doi:10.1038/s42003-025-07483-4

Chemical signals and social structures strengthen sexual isolation in Drosophila pseudoobscura

2025· article· en· W4406525618 on OpenAlexafffund
Jacob A. Jezovit, Joel D. Levine

Bibliographic record

VenueCommunications Biology · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInsect and Arachnid Ecology and Behavior
Canadian institutionsUniversity of Toronto
FundersCanada Research ChairsCanadian Institute for Advanced Research
KeywordsDrosophila pseudoobscuraIsolation (microbiology)Drosophila (subgenus)Social isolationBiologyEvolutionary biologyPsychologyGeneticsBioinformatics

Abstract

fetched live from OpenAlex

Species that coexist in hybrid zones sexually isolate through reproductive character displacement, a mechanism that favours divergence between species. In Drosophila, behavioural and physiological traits discourage heterospecific mating between species. Recently, social network analysis revealed flies produce strain-specific and species-specific social structures. A gene, degrees of kevin bacon (dokb) has also been discovered that accounts for differences in social structures between flies. Why differences in social structures exist between drosophilids is currently unknown. Here we show through an experimental evolution study that six generations of selection in experimental sympatry led to the divergence of social structures measured in Drosophila pseudoobscura and Drosophila persimilis flies. We found that the frequency of hybrid offspring decreased within a few generations, suggesting social structures are associated with the sexual isolation of species. We also report increased species' differences in the concentration of the cuticular hydrocarbon 5, 9-pentacosadiene after six generations of selection. The mean concentration of this compound converged in female flies of both species and diverged in male flies of both species, suggesting a quantitative link between increased sexual dimorphism and sexual isolation. Our results suggest that chemical signals, together with social structures, increase the sexual isolation between species in hybrid zones.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.317
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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