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Record W4406560048 · doi:10.1097/ms9.0000000000002928

Perioperative bowel regimens following posterior spinal fusions for adolescent idiopathic scoliosis: a systematic review

2025· review· en· W4406560048 on OpenAlexaff
Lee Benaroch, Ali Ahmadi Pirshahid, Kevin Morash, Supriya Singh, Parham Rasoulinejad, Debra Bartley, Timothy P. Carey, Alla Iansavitchene, Patrick Thornley

Bibliographic record

VenueAnnals of Medicine and Surgery · 2025
Typereview
Languageen
FieldMedicine
TopicScoliosis diagnosis and treatment
Canadian institutionsLondon Health Sciences CentreWestern University
Fundersnot available
KeywordsMedicinePerioperativeScoliosisSurgeryIdiopathic scoliosisSpinal fusionAnesthesia

Abstract

fetched live from OpenAlex

Background: Bowel morbidity after posterior spinal fusions (PSFs) for adolescent idiopathic scoliosis (AIS) delays the advancement of postoperative oral diet and discharge. This systematic review aims to investigate the effectiveness of perioperative bowel regimens in reducing length of stay and postoperative bowel morbidity in these patients. Materials and methods: We systematically searched MEDLINE, Embase, Cochrane, SPORTDiscus, and CINAHL for articles reporting on clinical results of PSFs for AIS patients. Demographic data, mean operative time and estimated blood loss, length of stay, time to first flatus and/or bowel movement, first oral intake, and postoperative pain scores were extracted from the selected studies. Results: Six articles (n = 468 patients) met the final inclusion criteria. Only one study, which assessed oral methylnaltrexone, reported a significant reduction in the mean hospital length of stay (0.60 days, P < 0.05) and postoperative abdominal distension (17% versus 40%, P < 0.05); however, it was also the only study to report a significantly increased mean operative time (38.9 min, P = 0.03) and estimated blood loss (111.1 mL, P = 0.05) compared to the treatment group. Time to flatus, regular diet, postoperative opioid consumption, and pain scores did not differ significantly in any of the reported studies. Conclusion: There is limited evidence to demonstrate any specific perioperative bowel regimen will decrease postpreparative bowel morbidity and/or length of stay. While not a treatment in isolation, oral methylnaltrexone may be a safe and effective adjunct to standard postoperative bowel regimens and may have a better patient tolerance profile.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.018
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.007
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.018
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0060.006
Bibliometrics0.0040.005
Science and technology studies0.0000.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.185
GPT teacher head0.441
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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